Tumor Cells’ Response to Treatment Is Driven by Randomness
Neuroblastoma cells (cyan) increasing as a tumor and the surrounding collagen matrix (magenta). The cells are expressing a biosensor (JNK-KTR) that reads out one-cell JNK activity in response to chemotherapy therapy. Credit: Max Nobis / Garvan Inherent ‘noise’ in the system of gene expression in tumor mobile dying, is an additional tool cancer cells use to resist chemotherapy procedure. Most cancers cells have an innate randomness in their capacity to respond to chemotherapy, which is a different resource in their…
