How to exercise when you have a chronic condition or a disability

How to exercise when you have a chronic condition or a disability

Editor’s Observe: Prior to starting any new workout method, talk to your doctor. Halt immediately if you practical experience ache.



CNN
 — 

Lots of men and women wrestle to maintain a standard exercise routine regimen. Increase in a incapacity, chronic affliction or injury, and it can be even a lot more complicated to include work out into a weekly regimen. Nonetheless it’s crucial to do so.

Older people with disabilities are 3 occasions much more probably to build major health and fitness disorders such as coronary heart ailment, stroke, diabetes and cancer than those without disabilities, according to the US Centers for Disease Manage and Prevention. When the effect of these health problems can be lessened or quite possibly even averted with standard aerobic physical exercise, practically 50 {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of adults ages 18 to 64 with a disability are not engaging in any, the CDC states.

“Regular physical exercise can present a lot of rewards for folks with disabilities, like improved all round health and fitness, elevated power and endurance, better mobility, and enhanced psychological overall health,” claimed Lalitha McSorley, operator and guide actual physical therapist at Brentwood Physiotherapy Clinic in Calgary, Alberta.

Frequent training can also support control the signs or symptoms affiliated with some disabilities. For instance, workout can minimize the discomfort and stiffness that typically accompanies arthritis, and it can increase cognitive operate in persons with cognitive troubles, she claimed. Moreover, a regular workout regime can increase self-esteem and give useful socialization and community engagement.

In 2020, the Planet Health and fitness Firm produced the initial world wide general public overall health suggestions about physical action for those with disabilities and chronic ailments, including diabetic issues, hypertension and most cancers. These pointers are the similar as the US Bodily Activity Rules for People for all older people: Just about every week you ought to do at the very least 150 to 300 minutes of average-depth cardio physical exercise, 75 to 150 minutes of vigorous-intensity cardio actual physical activity or an equal blend of each. In addition, you ought to carry out muscle-strengthening pursuits two or far more times for each week.

Which kinds of training are ideal and useful will rely upon your distinct health and fitness predicament. In normal, some good possibilities are swimming, going for walks, water aerobics, biking and seated exercises, stated Bishnu Pada Das, a licensed own trainer based in Kolkata, India. Examples of seated workouts incorporate working with a hand cycle and doing chair exercises with or devoid of weights.

Chair workout routines can be as simple as ability punches in which you punch your arms in front of you in an alternating trend, Das stated, or alternating kicks, which include keeping your chair for assistance, then alternating leg kicks. Even torso rotations are useful, twisting from aspect to side and working with your arms to assist with the rotations.

Aquatic activities, such as pool running, are recommended by physical therapist Dr. Heather Swain of Ally Total Physical Therapy in Toledo, Ohio.

Functions these as drinking water aerobics and pool functioning are favored by Dr. Heather Swain, a physical therapist at Ally Total Physical Treatment in Toledo, Ohio. “The decreased gravity with aquatic work out will help folks to be additional mobile,” Swain stated. “It can be empowering to see your physique transfer and execute movements you couldn’t outdoors of the drinking water.” The hydrostatic tension of the water also allows improve blood move and decreases irritation.

If you really do not have easy access to a pool, Swain considers yoga a wonderful, and generally underrated, alternative. Yoga can support preserve adaptability and equilibrium, no make a difference your skill degree, which minimizes your hazard of personal injury, she explained. In addition, the breath do the job concerned gains pelvic overall health, back again discomfort, cognitive functionality and psychological health and fitness.

These with joint concerns may possibly benefit extra from isometric workout routines in which you tighten a particular muscle or muscle mass teams. Imagine exercise routines these kinds of as planks, squats and wall sits. Isometric exercise routines support preserve muscle mass toughness although preventing further muscle deterioration.

If you have reduced-entire body troubles or are unsteady on your feet, chair aerobics are a superior choice. Applying quick, repetitive motions, these kinds of as performing bicep curls or marching in spot, chair aerobics exercises can loosen rigid joints when boosting your heart rate. Introducing in dumbbells or resistance bands incorporates energy education, way too. Accomplishing chair yoga, or even stretching through the working day, aids in adaptability and can enable decrease the agony and muscle strain that can come when you sit for long periods of time.

Incorporate muscle-strengthening exercises into your routine two or more days per week.

No make a difference what form of exercise you determine on, quite a few variables can assistance make sure your accomplishment. Timetable your exercises for the time of day you are inclined to sense greatest, said accredited personal coach Kelly Borowiec, founder of Keebs Fitness in Saratoga, California. It also aids to make confident you are as comfy as achievable whilst exercising.

“If you wrestle with arthritis, improve the space temperature wherever you are going to be doing exercises,” said Borowiec, who has comprehensive expertise performing with customers who have disabilities or prolonged-phrase injuries. “Set aims, way too, as acquiring a actual physical incapacity doesn’t suggest you just cannot make development. And emphasis on what you can do, rather than what you cannot do.”

Swain agreed. “It can be effortless to aim on your limitations,” she explained. “Exercising can remind you of what your human body can do, and can give you a sense of empowerment and accomplishment that is useful to your self-efficacy.”

Melanie Radzicki McManus is a freelance author who specializes in climbing, travel and fitness.

Amitabh Bachchan Health Update: ‘It shall take time.’ Amitabh Bachchan shares health update, says he will resume work once condition improves

Amitabh Bachchan Health Update: ‘It shall take time.’ Amitabh Bachchan shares health update, says he will resume work once condition improves
Bollywood megastar Amitabh Bachchan, who is recovering from a ‘muscle tear to the appropriate rib cage’, took to his weblog on Tuesday early morning to share an update with his fans.

Through the weekend, Bachchan explained that he endured accidents whilst shooting an action sequence on the sets of his upcoming film ‘Project K’ in Hyderabad. He claimed that his “rib cartilage popped broke” and there is a “muscle mass tear to the right rib cage.”

Sharing an update on his wellbeing, the 80-calendar year-previous explained that he was receiving superior “step by step” but it will just take some time. He has been following the doctors’ orders “diligently” and guaranteeing complete mattress purple.

The actor also verified that he has paused capturing for Nag Ashwin’s directorial, starring Prabhas and Deepika Padukone, and other jobs in his kitty till he fully recovers. ‘Project K’ will strike the theatres on January 12, 2024.

“I progress progressively .. it shall acquire time .. and what has been recommended by the medical doctors is getting adopted diligently .. relaxation and strapped upper body .. all get the job done has stopped and will only get started after the affliction increases and the healthcare presents an assurance,” he extra.

​Big B's noteAgencies

The actor had revealed that he was in discomfort and was enduring issues in motion and breathing. “.. certainly agonizing .. on movement and respiration .. will get some weeks they say right before some normalisation will take place .. some medication is also for discomfort .. (sic)”In the similar write-up, the actor also claimed that he is “cell a little bit for all the critical functions”.Ahead of returning to his Mumbai home ‘Jalsa’, Bachchan underwent a CT scan at a Hyderabad-based mostly hospital and the physicians suggested him bed relaxation.

Overcome with the messages and excellent needs, the veteran actor thanked his lovers, who he fondly calls his extended loved ones (Ef), for their prayers.

“To all that mail their issue on my harm, may well I convey my gratitude and like for your prayers … I am confused by the attention you give me and am so grateful to the relatives Ef for this embrace. But my enormous gratitude to all,” he wrote.

The Significant B also dropped a sequence of tweets on Twitter for his 48.3 million followers.

“Gratitude and like ever … for your worry and wishes. Your prayers are the cure. I relaxation and make improvements to with your prayers,” he wrote in a few diverse tweets.

https://twitter.com/SrBachchan/position/1632963435217448960

https://twitter.com/SrBachchan/standing/1632963581825146880

https://twitter.com/SrBachchan/position/1632963941352472576

Because of to his personal injury, Bachchan also couldn’t be a part of his supporters for his Sunday ritual of assembly and greeting admirers stationed exterior his Juhu bungalow.

IDEXX LABORATORIES INC /DE MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS (form 10-K)

IDEXX LABORATORIES INC /DE MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
OF OPERATIONS (form 10-K)
The following discussion and analysis of our financial condition and results of
operations should be read in conjunction with the consolidated financial
statements and related notes appearing elsewhere in this Annual Report on
Form 10­K. The discussion of our financial condition and results of operations
and liquidity and capital resources for the year ended December 31, 2020, and
year-over-year comparisons between 2021 and 2020, is included in our Annual
Report on Form 10-K for the year ended December 31, 2021, within Item 7.
Management's Discussion and Analysis of Financial Condition and Results of
Operations, and is incorporated by reference herein.

We have included certain terms and abbreviations used throughout this Annual
Report on Form 10-K in the “Glossary of Terms and Selected Abbreviations.”


Description of Business Segments. We operate primarily through three business
segments: diagnostic and information management-based products and services for
the companion animal veterinary industry, which we refer to as the Companion
Animal Group ("CAG"); water quality products ("Water"); and diagnostic products
and services for livestock and poultry health and to ensure the quality and
safety of milk and improve producer efficiency, which we refer to as Livestock,
Poultry and Dairy ("LPD"). Our Other operating segment combines and presents our
human medical diagnostic products and services business ("OPTI Medical") with
our out-licensing arrangements because they do not meet the quantitative or
qualitative thresholds for reportable segments. Refer to "Part II, Item 8.
Financial Statements and Supplementary Data, Note 3. Revenue Recognition and
Note 17. Segment Reporting" to the consolidated financial statements for the
year ended December 31, 2022, included in this Annual Report on Form 10-K for
financial information about our segments, including our product and service
categories, and our geographic areas.

The following is a discussion of the strategic and operating factors that we
believe have the most significant effect on the performance of our business.

Companion Animal Group


Our strategy is to provide veterinarians with the highest quality diagnostic
information, software products and services, and medical evidence to support
more advanced medical care and information management solutions that help
demonstrate the value of diagnostics to pet owners and enable efficient and
effective practice management. By doing so, we are able to build a mutually
successful relationship with our veterinarian customers based on healthy pets,
loyal customers, staff efficiency, and expanding practice revenues.

CAG Diagnostics. We provide diagnostic capabilities that meet veterinarians'
diverse needs through a variety of modalities including in-clinic diagnostic
solutions and outside reference laboratory services. Veterinarians that utilize
our full line of diagnostic modalities obtain a single view of a patient's
diagnostic results, which allows them to track and evaluate trends and achieve
greater medical insight.

Our diagnostic capabilities generate both recurring and non-recurring revenues.
Revenues related to capital placements of our in-clinic IDEXX VetLab suite of
instruments and our SNAP Pro Analyzer are non-recurring in nature in that they
are sold to a particular customer only once. Revenues from the associated IDEXX
VetLab consumables, SNAP rapid assay test kits, reference laboratory and
consulting services, and extended maintenance agreements and accessories related
to our IDEXX VetLab instruments and our SNAP Pro Analyzer are recurring in
nature, in that they are regularly purchased by our customers, typically as they
perform diagnostic testing as part of ongoing veterinary care services. Our
recurring revenues, most prominently IDEXX VetLab consumables and rapid assay
test kits, have significantly higher gross margins than those provided by our
instrument sales. Therefore, the mix of recurring and non-recurring revenues in
a particular period will impact our gross margins.

Diagnostic Capital Revenue. Revenues related to the placement of the IDEXX
VetLab suite of instruments are non-recurring in nature, in that the customer
will buy an instrument once over its respective product life cycle, but will
purchase consumables for that instrument on a recurring basis as they use that
instrument for testing purposes. During the early stage of an instrument's life
cycle, we derive relatively greater revenues from instrument placements, while
consumable sales become relatively more significant in later stages as the
installed base of instruments increases and instrument placement revenues begin
to decline. In the early stage of an instrument's life cycle, placements are
made primarily through sales transactions. As the demand for the product
matures, an increasing percentage of placements are made in transactions,
sometimes referred to as
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volume commitments, such as our IDEXX 360 program, or reagent rentals, in which
instruments are placed at customer sites at little or no cost in exchange for a
multi-year customer commitment to purchase recurring products and services.

Below is a table showing active installed base units of our premium diagnostic
instruments as of the years ended December 31, 2022, 2021, and 2020:


(units in thousands)                                                                        Installed Base
                      Instrument                                December 31, 2022             December 31, 2021          December 31, 2020
Catalyst                                                                        63.1                          56.6               49.7
Premium Hematology                                                              43.1                          38.2               34.6
SediVue                                                                         15.6                          13.2               10.7



Our long-term success in the continuing growth of our CAG recurring diagnostic
product and services is dependent upon: growing volumes at existing customers by
increasing their utilization of existing and new test offerings, acquiring new
customers, maintaining high customer loyalty and retention, and realizing modest
annual price increases based on our differentiated products and the growing
value of our diagnostic offering. We continuously seek opportunities to enhance
the care that veterinary professionals give to their patients and clients
through supporting the implementation of real-time care testing workflows, which
is performing tests and sharing test results with the client at the time of the
patient visit. Our latest generation of chemistry, hematology, and urinalysis
instruments demonstrates this commitment by offering enhanced ease of use,
faster time to results, broader test menu and connectivity to various
information technology platforms that enhance the value of the diagnostic
information generated by the instruments. In addition, we provide marketing
tools and customer support that help drive efficiencies in veterinary practice
processes and allow practices to increase the number of clients they see on a
daily basis.

With all of our instrument product lines, we seek to differentiate our products
from our competitors' products based on time-to-result, ease-of-use, throughput,
breadth of diagnostic menu, flexibility of menu selection, accuracy,
reliability, ability to handle compromised samples, analytical capability of
diagnostics software, integration with the IVLS and VetConnect PLUS, client
communications capabilities, education and training, and superior sales and
customer service. Our success depends, in part, on our ability to differentiate
our products in a way that justifies a premium price.

Recurring Diagnostic Revenue. Revenues from our IDEXX VetLab consumable
products, our SNAP rapid assay test kits, outside reference laboratory and
consulting services, and extended maintenance agreements and accessories related
to our CAG Diagnostics instruments are considered recurring in nature. For the
year ended December 31, 2022, recurring diagnostic revenue, which is both highly
durable and profitable, accounted for approximately 79{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of our
consolidated revenue.

Our in-clinic diagnostic solutions, consisting of our IDEXX VetLab consumable
products and SNAP rapid assay test kits, provide real-time reference lab quality
diagnostic results for a variety of companion animal diseases and health
conditions. Our outside reference laboratories provide veterinarians with the
benefits of a more comprehensive list of diagnostic tests and access to
consultations with board-certified veterinary specialists and pathologists,
combined with the benefit of same-day or next-day turnaround times.

We derive substantial revenues and margins from the sale of consumables that are
used in IDEXX VetLab instruments, and the multi-year consumable revenue stream
is significantly more valuable than the placement of the instrument. Our
strategy is to increase diagnostic testing within veterinary practices by
placing IDEXX VetLab instruments and increasing instrument utilization of
consumables. Utilization can increase due to a greater number of patient samples
being run or to an increase in the number of tests being run per patient sample.
Our strategy is to increase both drivers. To increase utilization, we seek to
educate veterinarians about best medical practices that emphasize the importance
of chemistry, hematology, and urinalysis testing for a variety of diagnostic
purposes, as well as by introducing new testing capabilities that were
previously not available to veterinarians.

Our in-clinic diagnostic solutions also include SNAP rapid assay tests that
address important medical needs for particular diseases prevalent in the
companion animal population. We seek to differentiate these tests from those of
other in-clinic test providers and reference laboratory diagnostic service
providers based on critically important sensitivity and specificity, as
demonstrated by peer-reviewed third-party research, as well as overall superior
performance and ease of use by providing our customers with combination tests
that test a single sample for up to six diseases at once, including the ability
to utilize our SNAP Pro Analyzer. We further augment our product development and
customer service efforts with sales and
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marketing programs that enhance medical awareness and understanding regarding
certain diseases and the importance of diagnostic testing.


The prevalence of in-clinic testing, as opposed to outside reference
laboratories such as IDEXX Reference Laboratories, may vary by region. We
attempt to differentiate our reference laboratory testing services from those of
competitive reference laboratories and competitive in-clinic offerings primarily
on the basis of a differentiated test menu, technology employed, quality,
turnaround time, customer service and tools such as VetConnect PLUS that
demonstrate the complementary manner in which our laboratory services work with
our in-clinic offerings.

Profitability in our lab business is supported, in part, by our expanding
business scale globally. Profit improvements also reflect benefits from price
increases and our ability to achieve operational efficiencies. When possible, we
utilize core reference laboratories to service samples from other states or
countries, expanding our customer reach without an associated expansion in our
reference laboratory footprint. New laboratories may operate at a loss until
testing volumes achieve sufficient scale. Acquired laboratories frequently
operate less profitably than our existing laboratories and acquired laboratories
may not achieve the profitability of our existing laboratory network for several
years until we complete the implementation of operating improvements and
efficiencies. Therefore, in the short term, new and acquired reference
laboratories generally may have a negative effect on our operating margin.

Recurring reference lab revenue growth is achieved both through increased
testing volumes with existing customers and through the acquisition of new
customers, net of customer losses. We believe the increased number of customer
visits by our sales professionals as a result of the growth in our field sales
organization has led to increased reference laboratory opportunities with
customers who already use one of our in-clinic diagnostic modalities. In recent
years, recurring reference laboratory diagnostic and consulting revenues have
also been increased through reference laboratory acquisitions, customer list
acquisitions, the opening of new reference laboratories, including laboratories
that are co-located with large practice customers, and as a result of our
up-front customer loyalty programs and our volume commitment programs. Our
up-front customer loyalty programs are associated with customer acquisitions and
retention and provide incentives to customers in the form of cash payments or
IDEXX Points upon entering multi-year contractual agreements to purchase annual
minimum amounts of products or services, including reference laboratory
services. Our volume commitment programs, such as IDEXX 360, provide customers
with a free or discounted instrument or system upon entering into multi-year
agreements to purchase annual minimum amounts of products and services.

Veterinary Software, Services and Diagnostic Imaging Systems. Our portfolio of
practice management offerings is designed to serve the full range of customers
primarily within the North American, Australian, New Zealand, and European
regions. Cornerstone, ezyVet, Animana, IDEXX Neo, and DVMAX practice management
systems provide superior integrated information solutions, backed by exceptional
customer support and education. These practice management systems allow the
veterinarian to practice better medicine and achieve the practice's business
objectives, including a quality client experience, staff efficiency and practice
effectiveness and profitability. We market Cornerstone, ezyVet, IDEXX Neo, and
DVMAX practice management systems to customers primarily in North America,
Australia, and New Zealand. We market our Animana offering to customers
primarily throughout Europe.

Animana, ezyVet, and IDEXX Neo practice management systems are
subscription-based SaaS offerings designed to provide flexible pricing and a
durable, recurring revenue stream, while utilizing cloud technology instead of a
client server platform. While we continue to support our licensed-based
Cornerstone and DVMAX software, we are growing our installed base of
subscription-based practice management offerings for new customers of IDEXX
practice management systems. We believe that once established, this
subscription-based model will provide higher profitability as compared to the
historical license-based placements. Our Cornerstone and DVMAX customer base
continues to be an important driver of growth through enhanced diagnostic
integrations and high value add-on subscription services, such as Pet Health
Network Pro, Petly Plans, and credit card processing, and we continue to make
investments to enhance the customer experience of all of our license-based
software offerings. We also offer rVetLink, a comprehensive referral management
solution for specialty care hospitals that streamlines the referral process
between primary care and specialty care veterinarians. rVetLink's cloud
technology integrates with major specialty hospital management systems,
including Cornerstone Software and DVMAX Software.

We differentiate our practice management systems through enhanced functionality,
ease of use, and embedded integration with in-clinic IDEXX VetLab instruments
and outside reference laboratory test results. Our client communication services
create more meaningful pet owner experiences through personalized communication.
With our SmartFlow and Vet Radar cloud technology, we are able to improve
overall patient management through coordination and tracking of every step in a
patient workflow. Pet Health Network Pro online client communication and
education service complements the entire IDEXX
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product offering by educating pet owners and building loyalty through engaging
the pet owner before, during and after the visit, thereby building client
loyalty and driving more patient visits.


Our diagnostic imaging systems offer a convenient radiographic solution that
provides superior image quality and the ability to share images with clients
virtually anywhere. IDEXX imaging software enables enhanced diagnostic features
and streamlined integration with our other products and services. Our digital
radiography systems, enables low-dose radiation image capture without
sacrificing clear, high-quality diagnostic images, reducing the risk posed by
excess radiation exposure for veterinary professionals. Placements of imaging
systems are important to the growth of revenue streams that are recurring in
nature, including extended maintenance agreements and IDEXX Web PACS, which is
our cloud-based SaaS offering for viewing, accessing, storing, and sharing
multi-modality diagnostic images. We derive relatively higher margins from our
subscription-based products. IDEXX Web PACS is integrated with Cornerstone,
ezyVet, IDEXX Neo, DVMAX, and IDEXX VetConnect PLUS to provide centralized
access to diagnostic imaging results alongside patient diagnostic results from
any internet connected device.

Water


Our strategy in the water testing business is to develop, manufacture, market
and sell products that test primarily for the presence of microbial
contamination in water matrices, including drinking water supplies, with
superior performance, supported by exceptional customer service. Our customers
primarily consist of water utilities, government laboratories and private
certified laboratories that highly value strong relationships and customer
support. We expect that future growth in this business will be partially
dependent on our ability to increase international sales. Growth also will be
dependent on our ability to enhance and broaden our product line. Most water
microbiological testing is driven by regulation, and, in many countries, a test
may not be used for compliance testing unless it has been approved by the
applicable regulatory body and integrated into customers' testing protocols. As
a result, we maintain an active regulatory program that involves applying for a
growing number of regulatory approvals in a number of countries, primarily in
Europe. Further, we seek to receive regulatory approvals from governing agencies
as a means to differentiate our products from the competition.

Livestock, Poultry and Dairy


We develop, manufacture, market, and sell a broad range of tests and perform
services for various livestock diseases and conditions, and have active research
and development and in-licensing programs in this area. Our strategy is to offer
differentiated tests with superior performance characteristics for use in
government programs to control or eradicate disease and disease outbreaks and in
livestock and poultry producers' disease, reproductive, and herd health and
production management programs. Our Alertys Ruminant Pregnancy Test, Rapid
Visual Pregnancy Test and Alertys On-Farm Pregnancy Test for cattle can detect
pregnancy 28 days after breeding. These tests provide a quick and accurate
identifier using whole blood samples.

Disease outbreaks are episodic and unpredictable, and certain diseases that are
prevalent at one time may be substantially contained or eradicated at a later
time. In response to outbreaks, testing initiatives may lead to exceptional
demand for certain products in certain periods. Conversely, successful
eradication programs may result in significantly decreased demand for certain
products. In addition, increases in government funding may lead to increased
demand for certain products and budgetary constraints may lead to decreased
demand for certain products. As result, the performance in certain sectors of
this business can fluctuate.

Our strategy in the dairy testing business is to develop, manufacture and sell
antibiotic residue and contaminant testing products that satisfy applicable
regulatory requirements or dairy processor standards for testing of milk and
provide reliable field performance. The manufacture of these testing products
leverages the SNAP platform and production assets that also support our rapid
assay business, which also leverages the SNAP platform. The dairy SNAP products
incorporate customized reagents for antibiotic and contaminant detection.

Other


OPTI Medical. Our strategy in the OPTI Medical business for the human market is
to develop, manufacture, and sell electrolyte and blood gas analyzers, and
related consumable products for the medical point-of-care diagnostics sector
worldwide, with a focus on small to mid-sized hospitals. We seek to
differentiate our products based on ease of use, convenience, international
distribution and service and instrument reliability. Similar to our veterinary
instruments and consumables strategy, a substantial portion of the revenues from
this product line is derived from the sale of consumables for use on the
installed base of electrolyte and blood gas analyzers. During the early stage of
an instrument's life cycle, relatively greater revenues are derived from
instrument placements, while consumable sales become relatively more significant
in later
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stages as the installed base of instruments increases and instrument placement
revenues begin to decline. Our long-term success in this area of our business is
dependent upon new customer acquisition, customer retention and increased
customer utilization of existing and new assays introduced on these instruments.

During 2020, we introduced the OPTI SARS-CoV-2 RT-PCR test kit for human
COVID-19 testing. A significant portion of the 2021 growth in our OPTI Medical
business was from revenue generated from the test kits and related laboratory
services. The amount of revenue from this product decreased in 2022, with less
demand for testing. We expect revenues from COVID-19 related testing products
and services to be inconsequential in 2023.

Our facility in Roswell, Georgia develops and manufactures the OPTI product
lines using the same or similar technology to support the electrolyte
requirements of certain CAG products. We leverage this facility's know-how,
intellectual property, and manufacturing capability to continue to expand the
menu and instrument capability of the VetStat and Catalyst platforms for
veterinary applications, while reducing our cost of consumables by leveraging
experience and economies of scale.

CRITICAL ACCOUNTING ESTIMATES AND ASSUMPTIONS


The discussion and analysis of our financial condition and results of operations
is based upon the consolidated financial statements, which have been prepared in
accordance with U.S. GAAP. The preparation of these financial statements
requires us to make estimates and judgments that affect the reported amounts of
assets, liabilities, revenues and expenses, and related disclosure of contingent
assets and liabilities. We evaluate our estimates on an ongoing basis. We base
our estimates on historical experience and on various assumptions that we
believe to be reasonable under the circumstances, the results of which form the
basis for making judgments about the carrying values of assets and liabilities
that are not readily apparent from other sources. Actual results may differ from
these estimates. Refer to "Part II, Item 8. Financial Statements and
Supplementary Data, Note 2. Summary of Significant Accounting Policies" to the
consolidated financial statements included in this Annual Report on Form 10-K
for a description of the significant accounting policies used in preparation of
these consolidated financial statements.

We believe the following critical accounting estimates and assumptions may have
a material impact on reported financial condition and operating performance and
involve significant levels of judgment to account for highly uncertain matters
or are susceptible to significant change.

Revenue Recognition


Refer to "Part II, Item 8. Financial Statements and Supplementary Data, Note 3.
Revenue Recognition" to the consolidated financial statements for the year ended
December 31, 2022, included in this Annual Report on Form 10-K for additional
information about our revenue recognition policy and criteria for recognizing
revenue.

We enter into contracts where customers purchase combinations of IDEXX products
and services. Determining whether products and services are considered distinct
performance obligations that should be accounted for separately requires
judgment. We determine the transaction price for a contract based on the total
consideration we expect to receive in exchange for the transferred goods or
services. To the extent the transaction price includes variable consideration,
such as volume rebates or expected price adjustments, we apply judgment in
constraining the estimated variable consideration due to factors that may cause
reversal of revenue recognized. We evaluate constraints based on our historical
and projected experience with similar customer contracts.

We allocate revenue to each performance obligation in proportion to the relative
standalone selling prices and recognize revenue when control of the related
goods or services is transferred for each obligation. We utilize the observable
standalone selling price when available, which represents the price charged for
the promised product or service when sold separately. When standalone selling
prices for our products or services are not directly observable, we determine
the standalone selling prices using relevant information available and apply
suitable estimation methods including, but not limited to, the cost plus a
margin approach.

Our up-front loyalty programs provide customers with incentives in the form of
cash payments or IDEXX Points upon entering into multi-year agreements to
purchase annual minimum amounts of future products or services. If a customer
breaches their agreement, they are required to refund all or a portion of the
up-front cash or IDEXX Points, or make other repayments, remedial actions, or
both. Up-front incentives to customers in the form of cash or IDEXX Points are
not made in exchange for distinct goods or services and are capitalized as
customer acquisition costs within other current and long-term assets, which are
subsequently recognized as a reduction to revenue over the term of the customer
agreement. If these up-front incentives are
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subsequently utilized to purchase instruments, we allocate total consideration,
including future committed purchases less up-front incentives and estimates of
expected price adjustments, based on relative standalone selling prices to
identified performance obligations and recognize instrument revenue and cost at
the time of installation and customer acceptance. We estimate, based on
historical experience, and apply judgment to predict the amounts of future
customer purchases and expected price adjustments related to these multi-year
agreements. Differences between estimated and actual customer purchases may
impact the timing and amount of revenue recognition during the term of the
customer contract, and a 10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} change in these estimates would have increased or
reduced deferred revenue and cumulative revenue related to these programs by
approximately $1.1 million at December 31, 2022.

Our volume commitment programs, such as our IDEXX 360 program, provide customers
with free or discounted instruments or systems upon entering into multi-year
agreements to purchase annual minimum amounts of products and services. We
allocate total consideration, including future committed purchases and expected
price adjustments, based on relative standalone selling prices to identified
performance obligations and recognize instrument revenue and cost at the time of
installation and customer acceptance in advance of billing the customer, which
is also when the customer obtains control of the instrument based on legal title
transfer. Our right to future consideration related to instrument revenue is
recorded as a contract asset within other current and long-term assets. The
contract asset is transferred to accounts receivable when customers are billed
for products and services over the term of the contract. We estimate, based on
historical experience, and apply judgment to predict the amounts of future
customer purchases and expected price adjustments related to these multi-year
agreements. Differences between estimated and actual customer purchases may
impact the timing and amount of revenue recognition during the term of the
customer contract, and a 10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} change in these estimates would have increased or
reduced contract assets and cumulative revenue related to these programs by
approximately $4.3 million at December 31, 2022.

Our instrument rebate programs require an instrument purchase and provide
customers the opportunity to earn future rebates based on the volume of products
and services they purchase over the term of the program. We account for the
customer's right to earn rebates on future purchases as a separate performance
obligation and determine the standalone selling price based on an estimate of
rebates the customer will earn over the term of the program. Total consideration
allocated to identified performance obligations is limited to goods and services
that the customer is presently obligated to purchase and does not include
estimates of future purchases that are optional. We allocate total consideration
to identified performance obligations, including the customer's right to earn
rebates on future purchases, which is deferred and subsequently recognized upon
the purchase of products and services, partly offsetting rebates as they are
earned. We estimate, based on historical experience, and apply judgment to
predict the amounts of future customer rebates related to these multi-year
agreements. Differences between estimated and actual customer rebates may impact
the timing and amount of revenue recognition during the term of the customer
contract, and a 10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} change in these estimates would have increased or reduced
deferred revenue and cumulative revenue related to these programs by
approximately $2.8 million at December 31, 2022.

Future market conditions and changes in product offerings may cause us to change
marketing strategies to increase or decrease customer incentive offerings,
possibly resulting in incremental reductions of revenue in future periods as
compared to reductions in the current or prior periods. Additionally, certain
customer programs require us to estimate, based on historical experience, and
apply judgment to predict the amounts of future customer purchases, customer
rebates and other incentive payments, and price adjustments related to
multi-year agreements. Differences between estimated and actual customer
purchases may impact the timing and amount of revenue recognition as described
above.

Valuation of Goodwill and Other Intangible Assets


A significant portion of the purchase price for acquired businesses is generally
assigned to intangible assets. Intangible assets other than goodwill are
initially valued at fair value. If a quoted price in an active market for the
identical asset is not readily available at the measurement date, the fair value
of the intangible asset is estimated based on discounted cash flows using market
participant assumptions, which are assumptions that are not specific to IDEXX.
The selection of appropriate valuation methodologies and the estimation of
discounted cash flows require significant assumptions about the timing and
amounts of future cash flows, risks, appropriate discount rates, and the useful
lives of intangible assets. When significant, we typically utilize independent
valuation experts to advise and assist us in determining the fair values of the
identified intangible assets acquired in connection with a business acquisition
and in determining appropriate amortization methods and periods for those
intangible assets. Goodwill is initially valued based on the excess of the
purchase price of a business combination over the fair value of acquired net
assets recognized and represents the future economic benefits arising from other
assets acquired that could not be separately identified and recognized.

We assess goodwill for impairment annually, at the reporting unit level, in the
fourth quarter and whenever events or circumstances indicate impairment may
exist. An impairment charge is recorded for the amount, if any, by which the
carrying
                                       39
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amount of goodwill exceeds its implied fair value. Our reporting units are the
individual product and service categories that comprise our CAG operating
segment, our Water and LPD operating segments and goodwill remaining from the
restructuring of our pharmaceutical business in the fourth quarter of 2008. A
substantial portion of the goodwill remaining from the pharmaceutical business,
included in our "Other Segment," is associated with intellectual property that
has been, or may be, licensed to third parties. Realization of this goodwill is
dependent upon the success of those third parties in developing and
commercializing products, which will result in our receipt of royalties and
other payments.

As part of our goodwill testing process, we evaluate factors specific to a
reporting unit as well as industry and macroeconomic factors that are reasonably
likely to have a material impact on the fair value of a reporting unit. Examples
of the factors considered in assessing the fair value of a reporting unit
include: the results of the most recent impairment test; the competitive
environment; the regulatory environment; the effects natural disasters;
anticipated changes in product, supply chain, or labor costs; revenue and
profitability trends and expectations; the consistency of cash flows; and
current and long-range financial forecasts. The long-range financial forecasts
of the reporting units, which are based upon management's long-term view of our
markets, are used by senior management and the Board of Directors to evaluate
operating performance.

In the fourth quarter of 2022, we performed a qualitative assessment of goodwill
impairment for all of our reporting units, except for Pharmaceutical Activities,
and concluded that it is not more likely than not that the fair value of any of
those reporting units is less than its carrying amount, including goodwill. We
maintain approximately $6.5 million of goodwill associated with Pharmaceutical
Activities, which comprises pharmaceutical intellectual property, out-licensing
arrangements, and certain retained drug delivery technologies from which we earn
royalty revenue. For our Pharmaceutical Activities, we performed a quantitative
assessment and concluded that the estimated fair value approximates the carrying
amount of the reporting unit. We estimated the fair value of the Pharmaceutical
Activities using an income approach based on discounted forecasted cash flows,
making assumptions about future cash flows and discount rates. These is no
guarantee that we will be able to maintain revenues from our remaining
Pharmaceutical Activities. No goodwill impairments were identified during the
years ended December 31, 2022, 2021, and 2020.

A prolonged economic downturn in the U.S. or internationally resulting in lower
long-term growth rates and reduced long-term profitability may reduce the fair
value of our reporting units. Industry specific events or circumstances could
have a negative impact on our reporting units and may also reduce the fair value
of our reporting units. Should such events occur, and it becomes more likely
than not that a reporting unit's fair value has fallen below its carrying value,
we will perform an interim goodwill impairment test, in addition to the annual
impairment test. Future impairment tests may result in an impairment of
goodwill. An impairment of goodwill would be reported as a non-cash charge to
earnings.

We also assess the realizability of intangible assets whenever events or changes
in circumstances indicate that the carrying value may not be recoverable. If an
impairment review is triggered, we evaluate the carrying value of intangible
assets, other than goodwill, based on estimated undiscounted future cash flows
over the remaining useful life of the primary asset of the asset group and
compare that value to the carrying value of the asset group. The asset group is
the lowest level for which identifiable cash flows associated with the
intangible asset are largely independent. The cash flows that are used contain
our best estimates, using appropriate and customary assumptions and projections
at the time. If the net carrying value of the asset group exceeds the related
estimated undiscounted future cash flows, an impairment loss to adjust the
intangible asset to its fair value would be reported as a non-cash charge to
earnings. If necessary, we would calculate the fair value of an intangible asset
using the present value of the estimated future cash flows to be generated by
the intangible asset and apply a risk-adjusted discount rate. We had no
impairments of our intangible assets during the years ended December 31, 2022
and 2021. The amount of impairment for the year ended December 31, 2020 was
immaterial.

Income Taxes


The provision for income taxes is determined using the asset and liability
approach of accounting for income taxes. Under this approach, deferred taxes
represent the estimated future tax effects of temporary differences between book
and tax treatment of assets and liabilities and carryforwards to the extent they
are realizable.

We assess our current and projected earnings by jurisdiction to determine
whether or not our earnings during the periods when the temporary differences
become deductible will be sufficient to realize the related future tax benefits.
Should we determine that we would not be able to realize all or part of our net
deferred tax asset in a particular jurisdiction in the future, an adjustment to
the deferred tax asset would be charged to income in the period such
determination was made.

For those jurisdictions where tax carryforwards are likely to expire unused or
the projected operating results indicate that realization is not more likely
than not, a valuation allowance is recorded to offset the deferred tax asset
within that
                                       40
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jurisdiction. In assessing the need for a valuation allowance, we consider
future taxable income and ongoing prudent and feasible tax planning strategies.
In the event that we determine that we would be able to realize our deferred tax
assets in the future in excess of the net recorded amount, a reduction of the
valuation allowance would increase income in the period such determination was
made. Likewise, should we determine that we would not be able to realize all or
part of our net deferred tax asset in the future, a reduction to the deferred
tax asset would be charged against income in the period such determination was
made.

Our net taxable temporary differences and tax carryforwards are recorded using
the enacted tax rates expected to apply to taxable income in the periods in
which the deferred tax liability or asset is expected to be settled or realized.
Should the expected applicable tax rates change in the future, an adjustment to
our deferred taxes would be credited or charged, as appropriate, to income in
the period such determination was made.

We periodically assess our exposures related to our worldwide provision for
income taxes and believe that we have appropriately accrued taxes for
contingencies. Any reduction of these contingent liabilities or additional
assessment would increase or decrease income, respectively, in the period such
determination was made.


We record a liability for uncertain tax positions that do not meet the more
likely than not standard as prescribed by the authoritative guidance for income
tax accounting. We record tax benefits for only those positions that we believe
will more likely than not be sustained. For positions that we believe that it is
more likely than not that we will prevail, we record a benefit considering the
amounts and probabilities that could be realized upon ultimate settlement. If
our judgment as to the likely resolution of the uncertainty changes, if the
uncertainty is ultimately settled or if the statute of limitation related to the
uncertainty expires, the effects of the change would be recognized in the period
in which the change, resolution or expiration occurs. Our net liability for
uncertain tax positions was $25.8 million as of December 31, 2022, and $25.5
million as of December 31, 2021, which includes estimated interest expense and
penalties. Refer to "Part II, Item 8. Financial Statements and Supplementary
Data, Note 14. Income Taxes" in the accompanying Notes to consolidated financial
statements for more information.

RECENT ACCOUNTING PRONOUNCEMENTS

Refer to “Part II, Item 8. Financial Statements and Supplementary Data, Note 2.
Summary of Significant Accounting Policies (v) and (w)” to the consolidated
financial statements for the year ended December 31, 2022, included in this
Annual Report on Form 10-K for a complete discussion of recent accounting
pronouncements adopted and not adopted.

RESULTS OF OPERATIONS AND TRENDS

Effects of Certain Factors on Results of Operations


CAG Trends. Global trends in companion animal healthcare, including growth in
demand for clinical services, continue to support solid growth for companion
animal diagnostic products and services across regions. In the U.S., average
diagnostics revenue per practice grew 6.9{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} on a same-store basis during 2022,
faster than 5.1{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} growth in overall clinic revenues. U.S. same-store clinical
visits at veterinary practices declined 2.3{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} in 2022, reflecting impacts this
year from reductions in veterinary clinic capacity levels and comparison to high
prior-year visit levels. Growth for pet healthcare including diagnostics remains
elevated compared to pre-pandemic levels reflecting compound annual growth of
2.9{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} in clinical visits and 11.2{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} in same-store diagnostics revenues for the
U.S. compared to 2019.

Supply Chain and Logistics Challenges. We believe that building and maintaining
a well-managed and disciplined infrastructure have helped minimize impacts of
the current supply chain constraints, including product and component
availability issues, logistics challenges, including extended shipping periods
and delays, and inflationary pressures that are currently occurring worldwide.
Our proactive approach to managing our operational processes, including forward
planning with a focus on working closely with our suppliers and logistics
partners, has enabled us to maintain continued high levels of product and
service availability and customer service. We continue to monitor these supply
chain and logistics challenges, including potential fuel rationing and
shortages, and have implemented mitigation strategies to adjust for, among other
things, delayed shipments of products and components. Although we expect these
challenges to continue during 2023, we believe we are well-positioned to enable
sustained high growth in our businesses going forward and to effectively manage
the impacts of potentially relatively higher costs in certain areas to support
these growth plans. However, there can be no assurance as to the duration or
severity of the supply chain and logistics challenges or the effectiveness of
our mitigating activities.

                                       41
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War in Ukraine / Russia Operations. Our operations in the Russia, Belarus, and
Ukraine region are limited, with no manufacturing or significant supply
arrangements. After significantly scaling back our operations in Russia in the
first quarter of 2022, including suspending sales of veterinary diagnostic
equipment; promotional, marketing, and hiring activities; and new business
development and related investments, we decided in June 2022 to wind down and
liquidate our sole Russian subsidiary, as well as our direct Russian operations,
which consisted of marketing and selling diagnostic products for veterinary
clinics in Russia. We anticipate that only a limited number of our products,
which are important for human or animal healthcare, will continue to be sold in
Russia pursuant to ongoing third-party distribution agreements. Some of our
products are also sold in Belarus pursuant to ongoing third-party distribution
agreements. Historical revenues from the Russia, Belarus, and Ukraine region
have been less than 1{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of our total consolidated revenue.

Distributor Purchasing and Inventories. When selling our products through
distributors, changes in distributors' inventory levels can impact our reported
sales, and these changes may be affected by many factors, which may not be
directly related to underlying demand for our products by veterinary practices,
which are the end users. If during the current year, distributors' inventories
grew by less than those inventories grew in the comparable period of the prior
year, then changes in distributors' inventories would have an unfavorable impact
on our reported sales growth in the current period. Conversely, if during the
current year, distributors' inventories grew by more than those inventories grew
in the comparable period of the prior year, then changes in distributors'
inventories would have a favorable impact on our reported sales growth in the
current period.

In certain countries, we sell our products through third-party distributors and
may be unable to obtain data for sales to end users. We do not believe the
impact of changes in these distributors’ inventories had or would have a
material impact on our growth rates. Refer to “Part I, Item 1. Business,
Marketing and Distribution” included in this Annual Report on Form 10-K for
additional information regarding distribution channels.


Currency Impact. For the year ended December 31, 2022, approximately 21{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of our
consolidated revenue was derived from products manufactured or sourced in U.S.
dollars and sold internationally in local currencies, as compared to 23{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} for the
year ended December 31, 2021 and 21{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} for the year ended December 31, 2020.
Strengthening of the rate of exchange for the U.S. dollar relative to other
currencies has a negative impact on our revenues derived in currencies other
than the U.S. dollar and on profits of products manufactured or purchased in
U.S. dollars and sold internationally, and a weakening of the U.S. dollar has
the opposite effect. Similarly, to the extent that the U.S. dollar is stronger
in current or future periods relative to the exchange rates in effect in the
corresponding prior periods, our growth rate will be negatively affected. The
impact of foreign currency denominated operating expenses and foreign currency
denominated supply contracts partly offsets this exposure. Additionally, our
designated hedges of intercompany inventory purchases and sales help delay the
impact of certain exchange rate fluctuations on non-U.S. denominated revenues.
Refer to "Part II, Item 7A. Quantitative and Qualitative Disclosures About
Market Risk" included in this Annual Report on Form 10-K for additional
information regarding currency impact. Our future income tax expense could also
be affected by changes in the mix of earnings, including as a result of changes
in the rate of exchange for the U.S. dollar relative to currencies in countries
with differing statutory tax rates. Refer to "Part I, Item 1A. Risk Factors"
included in this Annual Report on Form 10-K for additional information regarding
tax impacts.

Effects of Economic Conditions. Demand for our products and services is
vulnerable to changes in the economic environment, including slow economic
growth, high unemployment, and credit availability. Negative or cautious
consumer sentiment can lead to reduced or delayed consumer spending, resulting
in a decreased number of patient visits to veterinary clinics. Unfavorable
economic conditions can impact sales of instruments, diagnostic imaging, and
practice management systems, which are larger capital purchases for
veterinarians. Additionally, economic turmoil, fears of a global economic
downturn or recession, and inflationary pressure can cause our customers to
remain sensitive to the pricing of our products and services. In the U.S., we
monitor patient visits and clinic revenue data provided by a subset of our CAG
customers. Although this data is a limited sample and susceptible to short-term
impacts such as weather, which may affect the number of patient visits in a
given period, we believe that this data provides a fair and meaningful long-term
representation of the trend in patient visit activity in the U.S., providing us
insight regarding demand for our products and services.

Economic conditions can also affect the purchasing decisions of our Water and
LPD business customers. Water testing volumes may be susceptible to declines in
discretionary testing for existing home and commercial sales and in mandated
testing as a result of decreases in home and commercial construction. Testing
volumes may also be impacted by severe weather conditions such as drought. In
addition, fiscal difficulties can also reduce government funding for water and
herd health screening services.

We believe that the diversity of our products and services and the geographic
diversity of our customers partially mitigate the potential effects of the
economic environment and negative consumer sentiment on our revenue growth
rates.

                                       42
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Effects of Patent Expiration. Although we have several patents and licenses of
patents and technologies from third parties that expired during 2022, and
several that are expected to expire in 2023 and beyond, the expiration of these
patents or licenses, individually or in the aggregate, is not expected to have a
material effect on our financial position or future operations due to a range of
factors as described in "Part I, Item 1. Business, Patents and Licenses."

Non-GAAP Financial Measures. The following revenue analysis and discussion
focuses on organic revenue growth, and references in this analysis and
discussion to "revenue," "revenues" or "revenue growth" are references to
"organic revenue growth." Organic revenue growth is a non-GAAP financial measure
and represents the percentage change in revenue during the current year, as
compared to the same period for the prior year, net of the effect of changes in
foreign currency exchange rates, certain business acquisitions, and
divestitures. Organic revenue growth should be considered in addition to, and
not as a replacement for, or as a superior measure to, revenues reported in
accordance with U.S. GAAP, and may not be comparable to similarly titled
measures reported by other companies. Management believes that reporting organic
revenue growth provides useful information to investors by facilitating easier
comparisons of our revenue performance with prior and future periods and to the
performance of our peers.

We exclude from organic revenue growth the effect of changes in foreign currency
exchange rates because changes in foreign currency exchange rates are not
under management's control, are subject to volatility and can obscure underlying
business trends. We calculate the impact on revenue resulting from changes in
foreign currency exchange rates by applying the difference between the weighted
average exchange rates during the current year period and the comparable prior
year period to foreign currency denominated revenues for the prior year period.

We also exclude from organic revenue growth the effect of certain business
acquisitions and divestitures because the nature, size and number of these
transactions can vary dramatically from period to period, and because they
either require or generate cash as an inherent consequence of the transaction,
and therefore can also obscure underlying business and operating trends. We
consider acquisitions to be a business when all three elements of inputs,
processes and outputs are present, consistent with ASU 2017-01, "Business
Combinations: (Topic 805) Clarifying the Definition of a Business." In a
business combination, if substantially all the fair value of the assets acquired
is concentrated in a single identifiable asset or group of similar identifiable
assets, we do not consider these assets to be a business. A typical acquisition
that we do not consider a business is a customer list asset acquisition, which
does not have all elements necessary to operate a business, such as employees or
infrastructure. We believe the efforts required to convert and retain these
acquired customers are similar in nature to our existing customer base and
therefore are included in organic revenue growth.

We also use Adjusted EBITDA, gross debt, net debt, gross debt to Adjusted EBITDA
ratio and net debt to Adjusted EBITDA ratio, all of which are non-GAAP financial
measures that should be considered in addition to, and not as a replacement for,
financial measures presented according to U.S. GAAP. Management believes that
reporting these non-GAAP financial measures provides supplemental analysis to
help investors further evaluate our business performance and available borrowing
capacity under our Credit Facility.

Comparisons to Prior Periods. Our fiscal years end on December 31. Unless
otherwise stated, the analysis and discussion of our financial condition,
results of operations and liquidity, including references to growth and organic
growth and increases and decreases, are being compared to the equivalent prior
year period.



                                       43
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Twelve Months Ended December 31, 2022, Compared to Twelve Months Ended December
31, 2021


Total Company

The following table presents revenue by operating segment by U.S. and non-U.S.,
or international geographies:

                                          For the Years Ended December 31,
Net Revenue                                                                                                   Reported Revenue       Percentage Change         Percentage Change         Organic Revenue
(dollars in thousands)                        2022                    2021              Dollar Change            Growth (1)            from Currency           from Acquisitions            Growth (1)

CAG                                   $       3,058,793          $ 2,889,960          $      168,833                   5.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (3.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                8.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
United States                                 2,073,222            1,881,887                 191,335                  10.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                     -                         0.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                9.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
International                                   985,571            1,008,073                 (22,502)                 (2.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                 (9.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                6.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

Water                                 $         155,720          $   146,505          $        9,215                   6.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (4.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                9.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
United States                                    76,875               70,654                   6,221                   8.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                     -                           -                   8.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
International                                    78,845               75,851                   2,994                   3.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (7.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     1.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}               10.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

LPD                                   $         122,607          $   135,887          $      (13,280)                 (9.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                 (5.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                  (4.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
United States                                    16,633               15,626                   1,007                   6.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                     -                           -                   6.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
International                                   105,974              120,261                 (14,287)                (11.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                 (6.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                  (5.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})

Other                                 $          30,204          $    43,008          $      (12,804)                (29.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                  0.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                        -                 (30.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})

Total Company                         $       3,367,324          $ 3,215,360          $      151,964                   4.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (3.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                7.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
United States                                 2,182,959            1,995,683                 187,276                   9.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                     -                         0.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                8.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
International                                 1,184,365            1,219,677                 (35,312)                 (2.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                 (8.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                5.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

(1)Reported revenue growth and organic revenue growth may not recalculate due to
rounding.


Total Company Revenue. The increase in organic revenue reflects higher realized
prices and continued demand for companion animal diagnostics globally, supported
by higher CAG Diagnostics recurring revenue, primarily in the U.S. Increases in
our subscription-based veterinary software and diagnostic imaging services also
contributed to higher revenue for the year. The higher revenue in our Water
business was primarily due to the benefit of price increases and higher testing
volumes. The decline in our LPD business was primarily due to lower demand in
the first half of the year for swine testing in China, compared to high prior
year levels. The decrease in Other revenue reflects lower sales of OPTI COVID-19
PCR testing products. The impact of currency movements decreased total revenue
growth by 3.4{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}, while the impact of acquisitions increased total revenue growth
by 0.7{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.
                                       44
--------------------------------------------------------------------------------

The following table presents our total Company results of operations:

                                                                   For the Years Ended December 31,                                               Change
Total Company - Results of
Operations                                                            Percent of                                Percent of
(dollars in thousands)                           2022                  Revenue                2021               Revenue              Amount             Percentage

Revenues                                  $      3,367,324                               $ 3,215,360                               $ 151,964                     4.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Cost of revenue                                  1,362,986                                 1,325,928                                  37,058                     2.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Gross profit                                     2,004,338                 59.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         1,889,432                 58.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         114,906                     6.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

Operating Expenses:
Sales and marketing                                524,505                 15.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           486,735                 15.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          37,770                     7.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
General and administrative                         326,248                  9.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           309,660                  9.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          16,588                     5.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Research and development                           254,820                  7.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           161,009                  5.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          93,811                    58.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Total operating expenses                         1,105,573                 32.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           957,404                 29.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         148,169                    15.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Income from operations                    $        898,765                 26.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $   932,028                 29.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $ (33,263)                   (3.6) {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}



Gross Profit. Gross profit increased due to higher sales volumes and
a 70 basis point increase in the gross profit margin. The impact from foreign
currency movements increased the gross profit margin by approximately 50 basis
points, primarily from the impact of hedge gains in the current year as compared
to hedge losses in the prior year. Excluding the impact of foreign currency
movements, the increase in the gross margin was primarily due to net price
gains, improved software services gross margins, and the benefit of our
reference laboratory productivity initiatives. These increases were partially
offset by higher freight and distribution costs; higher service costs, including
increases in labor and facility costs; and higher product costs.

Operating Expenses. Sales and marketing expense increased primarily due to
higher personnel-related and travel costs, including investments in our global
commercial capability. General and administrative expense increased primarily
due to higher personnel-related costs, increase in allowances for doubtful
accounts receivable, and increases in amortization and depreciation expense
related to business acquisitions and capital investments. General and
administrative expense increases were partially offset by a comparative decrease
due to acquisition-related costs incurred in the prior year. Research and
development expense increased primarily due to discrete investments for the
acquisition of rights to use certain licensed technology under intellectual
property licensing arrangements, project costs, and higher personnel-related
costs. The overall change in foreign currency exchange rates resulted in a
decrease in operating expenses growth by approximately 2{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.
                                       45
--------------------------------------------------------------------------------

Companion Animal Group


The following table presents revenue by product and service category for CAG:

                                 For the Years Ended December 31,
Net Revenue                                                                                          Reported Revenue       Percentage Change         Percentage Change         Organic Revenue
(dollars in thousands)               2022                    2021              Dollar Change            Growth (1)            from Currency           from Acquisitions           Growth (1)

CAG Diagnostics
recurring revenue:           $       2,660,280          $ 2,534,562          $      125,718                   5.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (3.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                8.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
IDEXX VetLab
consumables                          1,057,236            1,006,781                  50,455                   5.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (4.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                   9.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Rapid assay products                   313,667              296,852                  16,815                   5.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (1.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                   7.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Reference laboratory
diagnostic and
consulting services                  1,178,113            1,123,656                  54,457                   4.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (2.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                7.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
CAG Diagnostics
services and
accessories                            111,264              107,273                   3,991                   3.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (4.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                   8.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
CAG Diagnostics
capital - instruments                  147,326              149,140                  (1,814)                 (1.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                 (4.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                       -                   3.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Veterinary software,
services and
diagnostic imaging
systems                                251,187              206,258                  44,929                  21.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (1.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     7.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}               14.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Net CAG revenue              $       3,058,793          $ 2,889,960          $      168,833                   5.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                  (3.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})                     0.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}                8.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

(1)Reported revenue growth and organic revenue growth may not recalculate due to
rounding.


CAG Diagnostics Recurring Revenue. The increase in CAG Diagnostics recurring
revenue was primarily due to higher realized prices and increased volumes in
IDEXX VetLab consumables, reference laboratory diagnostic services, and, to a
lesser extent, rapid assay products. The impact of foreign currency movements
decreased CAG Diagnostics recurring revenue growth by 3.4{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.

The increase in IDEXX VetLab consumables revenue was primarily due to higher
price realization and higher sales volumes, primarily of our Catalyst
consumables and, to a lesser extent, ProCyte consumables. These volume increases
were supported by the expansion of our installed base of instruments, our
expanded menu of available tests in certain regions, and high customer retention
levels. The impact of currency movements decreased revenue growth by 4.3{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.

The increase in rapid assay revenue resulted primarily from higher price
realization and higher clinic testing levels, primarily from SNAP 4Dx Plus. The
impact of currency movements decreased revenue growth by 1.7{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.


The increase in reference laboratory diagnostic and consulting services revenue
was primarily due to higher testing volumes and price realization in our U.S.
labs. Growth in other regions was primarily due to higher price realization,
partially offset by moderately lower international volumes compared to strong
prior period demand levels. Acquisitions increased revenue growth by 0.3{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. The
impact of currency movements decreased revenue growth by 2.9{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.

CAG Diagnostics services and accessories revenue growth was primarily a result
of the increase in our active installed base of instruments.


CAG Diagnostics Capital - Instrument Revenue. The impact of currency movements
decreased revenue growth by 4.7{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. Excluding the impact of currency, the growth
in instrument revenue was primarily due to higher premium instrument placements,
primarily of the ProCyte One analyzer, to support increased diagnostic testing.

Veterinary Software, Services, and Diagnostic Imaging Systems Revenue. The
acquired business increased revenue growth by 7.9{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. Excluding the impact of the
acquisition, the increase in veterinary software and services revenue was
primarily due to higher realized prices on service offerings and higher
subscription-based service revenue supported by the expansion in our active
installed base. The increase in our diagnostic imaging systems revenue was
primarily due to increases in our active installed base resulting in higher
service revenue, as well as higher instrument and equipment placements and
higher realized prices.

                                       46
--------------------------------------------------------------------------------

The following table presents the CAG segment results of operations:


                                                                           For the Years Ended December 31,                                               Change
Results of Operations                                                         Percent of                                Percent of
(dollars in thousands)                                   2022                  Revenue                2021               Revenue              Amount             Percentage

Revenues                                          $      3,058,793                               $ 2,889,960                               $ 168,833                     5.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Cost of revenue                                          1,252,216                                 1,206,156                                  46,060                     3.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Gross profit                                             1,806,577                 59.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         1,683,804                 58.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         122,773                     7.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

Operating Expenses:
Sales and marketing                                        480,655                 15.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           444,694                 15.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          35,961                     8.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
General and administrative                                 288,746                  9.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           274,470                  9.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          14,276                     5.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Research and development                                   236,227                  7.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           140,618                  4.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          95,609                    68.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Total operating expenses                                 1,005,628                 32.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           859,782                 29.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         145,846                    17.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Income from operations                            $        800,949                 26.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $   824,022                 28.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $ (23,073)                   (2.8) {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}



Gross Profit. Gross profit increased primarily due to higher sales volumes, as
well as an 80 basis point increase in the gross profit margin. The increase in
the gross profit margin was primarily due to recurring revenue net price gains,
improved software services gross margins, and the benefit of our reference
laboratory productivity initiatives. These increases were partially offset by
higher freight and distribution costs, higher product costs, and higher service
costs, including increases in labor and facility costs. The impact from foreign
currency movements increased the gross profit margin by approximately 30 basis
points, primarily from the impact of hedge gains in the current year as compared
to hedge losses in the prior year.

Operating Expenses. Sales and marketing expense increased primarily due to
higher personnel-related and travel costs, including investments in our global
commercial capability. General and administrative expense increased primarily
due to higher personnel-related costs, increases in amortization and
depreciation expense related to business acquisitions and capital investments,
and an increase in allowances for doubtful accounts receivable. General and
administrative expense increases were partially offset by a comparative decrease
due to acquisition-related costs incurred in the prior year. Research and
development expense increased primarily due to discrete investments for the
acquisition of rights to use certain licensed technology under intellectual
property licensing arrangements, project costs, and higher personnel-related
costs. The overall change in foreign currency exchange rates resulted in a
decrease in operating expenses growth by approximately 2{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.
                                       47
--------------------------------------------------------------------------------

Water

The following table presents the Water segment results of operations:


                                                                         For the Years Ended December 31,                                             Change
Results of Operations                                                        Percent of                              Percent of
(dollars in thousands)                                   2022                 Revenue               2021              Revenue             Amount            Percentage

Revenues                                          $       155,720                               $ 146,505                               $ 9,215                     6.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Cost of revenue                                            45,861                                  45,561                                   300                     0.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Gross profit                                              109,859                 70.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         100,944                 68.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         8,915                     8.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}

Operating Expenses:
Sales and marketing                                        18,564                 11.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          17,814                 12.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           750                     4.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
General and administrative                                 14,353                  9.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          13,442                  9.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           911                     6.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Research and development                                    4,423                  2.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           4,244                  2.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           179                     4.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Total operating expenses                                   37,340                 24.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          35,500                 24.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         1,840                     5.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Income from operations                            $        72,519                 46.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $  65,444                 44.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $ 7,075                    10.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}


Revenue. The increase in our Water business was due to higher realized prices
and testing volumes, primarily in our Colilert test products and related
accessories used in coliform and E. coli testing. The impact of currency
movements decreased revenue growth by 4.0{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. The impact of an acquisition
completed during the third quarter of 2022 increased revenue growth by 0.5{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.


Gross Profit. Gross profit for Water increased due to higher sales volumes and a
160 basis point increase in the gross profit margin, which reflected a 210 basis
point increase due to foreign currency movements, primarily from the impact of
hedge gains in the current year compared to hedge losses in the prior year.
Decreases in the gross profit margin were primarily due to higher product costs
and higher distribution and freight costs, partially offset by higher realized
prices.

Operating Expenses. Sales and marketing expense increased primarily due to
higher personnel-related and travel costs. General and administrative expense
increased primarily due to higher third-party service costs, including
acquisition-related costs, personnel-related costs, and allowances for doubtful
accounts receivable. Research and development expense increased primarily due to
higher personnel-related costs. The overall change in foreign currency exchange
rates resulted in a decrease in operating expenses growth by approximately 2{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.

                                       48
--------------------------------------------------------------------------------

Livestock, Poultry and Dairy

The following table presents the LPD segment results of operations:


                                                                         For the Years Ended December 31,                                              Change
Results of Operations                                                        Percent of                              Percent of
(dollars in thousands)                                   2022                 Revenue               2021              Revenue              Amount             Percentage

Revenues                                          $       122,607                               $ 135,887                               $ (13,280)                  (9.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Cost of revenue                                            49,606                                  54,323                                  (4,717)                  (8.7  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Gross profit                                               73,001                 59.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          81,564                 60.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          (8,563)                 (10.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})

Operating Expenses:
Sales and marketing                                        23,491                 19.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          21,681                 16.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           1,810                    8.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
General and administrative                                 17,119                 14.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          17,606                 13.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}            (487)                  (2.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Research and development                                   12,582                 10.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          13,641                 10.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          (1,059)                  (7.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Total operating expenses                                   53,192                 43.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          52,928                 39.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}             264                    0.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Income from operations                            $        19,809                 16.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $  28,636                 21.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $  (8,827)                 (30.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})




Revenue. The unfavorable impact of foreign currency movements decreased revenue
growth by 5.8{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. Excluding the impact of foreign currency, the decline in revenue
was primarily due to lower demand for diagnostic testing in China. Beginning
during the second quarter of 2021 and continuing through the first half of 2022,
we experienced lower livestock testing volumes in China, as changes in disease
management approaches, low pork prices, and changes in government requirements
related to the live animal imports and livestock infectious disease programs
impacted testing volumes, in comparison to high prior-year demand for African
Swine Fever testing. These declines were moderated during the second half of
2022, with modest volume increases in our swine testing market in China compared
to low prior year levels. The decrease in revenue was partially offset by higher
herd health screening in other Asia Pacific markets and higher price gains.

Gross Profit. The decrease in LPD gross profit was primarily due to lower sales
volumes and a 50 basis point decrease in the gross profit margin. The decrease
in the gross profit margin is primarily due to higher freight and distribution
costs, investments in our bovine laboratory services, the unfavorable overall
mix impacts largely from lower African Swine Fever testing, and higher product
costs. The decrease in the gross profit margin was partially offset by the
impact from foreign currency movements, which increased the gross profit margin
by approximately 360 basis points, primarily from the impact of hedge gains in
the current year compared to hedge losses in the prior year.

Operating Expenses. Sales and marketing expense increased primarily due to
increases in personnel-related and travel costs. General and administrative
decreased primarily due to lower personnel-related costs. Research and
development expenses decreased primarily due to lower personnel-related costs.
The overall change in foreign currency exchange rates resulted in a decrease in
operating expenses growth by approximately 4{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.
                                       49
--------------------------------------------------------------------------------

Other

The following table presents the Other results of operations:


                                                                      For the Years Ended December 31,                                          Change
Results of Operations                                                  Percent of                             Percent of
(dollars in thousands)                                2022              Revenue              2021              Revenue              Amount             Percentage

Revenues                                          $  30,204                               $ 43,008                               $ (12,804)                 (29.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Cost of revenue                                      15,303                                 19,888                                  (4,585)                 (23.1  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Gross profit                                         14,901                 49.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}         23,120                 53.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          (8,219)                 (35.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})

Operating Expenses:
Sales and marketing                                   1,795                  5.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          2,546                  5.9  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}            (751)                 (29.5  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
General and administrative                            6,030                 20.0  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          4,142                  9.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}           1,888                   45.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Research and development                              1,588                  5.3  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          2,506                  5.8  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}            (918)                 (36.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})
Total operating expenses                              9,413                 31.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}          9,194                 21.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}             219                    2.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}
Income from operations                            $   5,488                 18.2  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $ 13,926                 32.4  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}       $  (8,438)                 (60.6  {35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc})



Revenue. The decrease in Other revenue was primarily due to lower sales of OPTI
COVID-19 PCR testing products and services in the U.S. and, to a lesser extent,
lower OPTI Medical consumables revenue internationally. The impact of currency
movements increased revenues by 0.2{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}.

Gross Profit. Gross profit decreased due to lower sales volume and a 450 basis
point decrease in the gross profit margin. The decrease in the gross profit
margin was primarily due to unfavorable product mix with lower OPTI Medical
consumables and higher freight, distribution, and product costs, partially
offset by lower service costs associated with lower disease testing services.
The overall change in foreign currency exchange rates had an immaterial impact
on gross profit.

Operating Expenses. Sales and marketing expense decreased primarily due to lower
personnel-related costs. General and administrative expense increased primarily
due to higher foreign exchange losses on settlements of foreign currency
denominated transactions, as compared to the prior year, as well as higher
allowances for doubtful accounts receivable. Foreign exchange losses on
settlements for all operating segments are reported within our Other segment.
Research and development expense decreased primarily due to lower project costs
compared to investments in the development of infectious disease tests during
the prior year.

Non-Operating Items

Interest Expense. Interest expense was $39.9 million for the year ended December
31, 2022
, as compared to $29.8 million for the prior year. The increase in
interest expense was primarily the result of higher average debt levels.


Our effective income tax rate was 21.0{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} for the year ended December 31, 2022,
and 17.5{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} for the year ended December 31, 2021. The increase in our effective
tax rate was primarily driven by decreases in tax benefits related to
share-based compensation and higher taxes on international income. Our projected
effective tax rate for 2023 is approximately 22{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}. This projected 1{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} increase in
the effective tax rate, over the full year 2022 effective tax rate, is primarily
due to lower estimated tax benefits from share-based compensation.


                                       50
--------------------------------------------------------------------------------

LIQUIDITY AND CAPITAL RESOURCES


We fund the capital needs of our business through cash on hand, funds generated
from operations, proceeds from long-term senior note financings, and amounts
available under our Credit Facility. We generate cash primarily through the
payments made by customers for our companion animal veterinary, livestock,
poultry, dairy, and water products and services, consulting services, and other
various systems and services. Our cash disbursements are primarily related to
compensation and benefits for our employees, inventory and supplies, taxes,
research and development, capital expenditures, rents, occupancy-related
charges, interest expense, and business acquisitions. At December 31, 2022, we
had $112.5 million of cash and cash equivalents, as compared to $144.5 million
on December 31, 2021. Working capital, including our Credit Facility, totaled
negative $134.3 million at December 31, 2022, as compared to $192.1 million at
December 31, 2021. Additionally, at December 31, 2022, we had a remaining
borrowing availability of $669.5 million under our $1.25 billion Credit Facility
with $579.0 million outstanding borrowing under the Credit Facility. The general
availability of funds under our Credit Facility is reduced by $1.5 million for
outstanding letters of credit. We believe that, if necessary, we could obtain
additional borrowings to fund our growth objectives. We further believe that
current cash and cash equivalents, funds generated from operations, and
committed borrowing availability will be sufficient to fund our operations,
capital purchase requirements, and anticipated growth needs for the next twelve
months. We believe that these resources, coupled with our ability, as needed, to
obtain additional financing, will also be sufficient to fund our business as
currently conducted for the foreseeable future. We may enter into new financing
arrangements or refinance or retire existing debt in the future depending on
market conditions. Should we require more capital in the U.S. than is generated
by our operations, for example to fund significant discretionary activities, we
could elect to raise capital in the U.S. through the incurrence of debt or
equity issuances, which we may not be able to complete on favorable terms or at
all. In addition, these alternatives could result in increased interest expense
or other dilution of our earnings.

We manage our worldwide cash requirements considering available funds among all
of our subsidiaries. Our foreign cash and cash equivalents are generally
available without restrictions to fund ordinary business operations outside the
U.S.

The following table presents cash, cash equivalents and marketable securities
held domestically, and by our foreign subsidiaries:


                                                                    For the Years Ended December 31,
Cash and cash equivalents
(in thousands)                                                          2022                2021

U.S.                                                               $    16,112          $    2,632
Foreign                                                                 96,434             141,822
Total                                                              $   112,546          $  144,454

Total cash, cash equivalents and marketable securities held
in U.S. dollars by our foreign subsidiaries

                        $     

6,647 $ 6,245




As of December 31, 2022 and 2021, more than 99{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of the cash and cash equivalents
held was as bank deposits. Cash and cash equivalents at December 31, 2022,
included approximately USD $2.9 million of cash held in countries with currency
control restrictions, which limit our ability to transfer funds outside of the
country in which they are held. The currency control restricted cash is
generally available for use within the country where it is held.

The following table presents additional key information concerning working
capital:

                                                                                              For the Three Months Ended
                                                     December 31,             September 30,             June 30,              March 31,             December 31,
                                                         2022                     2022                    2022                  2022                    2021

Days sales outstanding (1)                                43.4                     43.4                    43.2                  42.0                     42.4
Inventory turns (2)                                        1.3                      1.3                     1.5                   1.6                      2.0


(1)   Days sales outstanding represents the average of the accounts receivable
balances at the beginning and end of each quarter divided by revenue for that
quarter, the result of which is then multiplied by 91.25 days.
(2)   Inventory turns represent inventory-related cost of product revenue for
the 12 months preceding each quarter-end divided by the average inventory
balances at the beginning and end of each quarter.

                                       51
--------------------------------------------------------------------------------

The decrease in inventory turns over the current year was a result of larger
inventory on-hand, as we have increased inventory to support demand and product
availability, as well as new product launches.

Sources and Uses of Cash

The following table presents cash provided (used):


(in thousands)                                                            

For the Years Ended December 31,

                                                                  2022                 2021              Dollar Change

Net cash provided by operating activities                   $   542,984            $  755,546          $     (212,562)
Net cash used by investing activities                          (195,350)             (292,967)                 97,617
Net cash used by financing activities                          (370,936)             (697,414)                326,478
Net effect of changes in exchange rates on cash                  (8,606)               (4,639)                 (3,967)
Net change in cash and cash equivalents                     $   (31,908)    

$ (239,474) $ 207,566




Operating Activities. The decrease in cash provided by operating activities of
$212.6 million during 2022 as compared to 2021, was primarily due to the lower
net income and changes in other assets and liabilities. During 2022, we entered
into two discrete arrangements to license intellectual property for which we
paid $65 million which was charged to research and development expense. We also
had an increase in taxes paid during 2022, primarily due to changes imposed by
the 2017 Tax Cuts and Jobs Act, including the relevant provision that requires
U.S. research and development expenditures incurred after January 1, 2022, to be
capitalized and amortized over a five-year period.

The following table presents cash flows (used) provided from changes in
operating assets and liabilities:


(in thousands)                                                           

For the Years Ended December 31,

                                                                 2022                 2021              Dollar Change

Accounts receivable                                         $    (41,398)         $  (33,141)         $       (8,257)
Inventories                                                     (121,731)            (52,919)                (68,812)
Accounts payable                                                   3,467              11,233                  (7,766)
Deferred revenue                                                 (11,019)             (7,551)                 (3,468)
Other assets and liabilities                                    (102,849)            (55,145)                (47,704)
Total change in cash due to changes in operating
assets and liabilities                                      $   (273,530)         $ (137,523)         $     (136,007)



Cash used due to changes in operating assets and liabilities during the year
ended December 31, 2022, as compared to the same period in the prior year,
increased approximately $136.0 million. Cash used for inventory in the current
period, as compared to the prior period, was higher primarily due to planned
inventory growth to support demand and product availability. The increase of
cash used for other assets and liabilities was primarily due to lower non-cash
operating expenses recorded as accrued liabilities, primarily for
personnel-related costs, as compared to the same period in the prior year,
partially offset by accrued research and development investments in the current
year.

We have historically experienced proportionally lower net cash flows from
operating activities during the first quarter and proportionally higher cash
flows from operating activities for the remainder of the year and for the annual
period driven primarily by payments related to annual employee incentive
programs in the first quarter following the year for which the bonuses were
earned.

Investing Activities. Cash used by investing activities was $195.4 million
during 2022 as compared to $293.0 million used during 2021. The decrease in cash
used by investing activities during 2022 as compared to 2021 was primarily due
to the acquisition of ezyVet during the second quarter of 2021, partially offset
by an acquisition of an intangible asset during the first quarter of 2022, an
equity investment during the second quarter of 2022, and the acquisition of a
water testing business in the third quarter of 2022, as well as the increase in
purchases of property and equipment related to our new warehouse and
manufacturing site expansion.

Our total capital expenditure plan for 2023 is estimated to be approximately
$180.0 million, which includes capital investments in manufacturing and
operations facilities to support growth, as well as investments in
customer-facing software.

                                       52
--------------------------------------------------------------------------------

Financing Activities. Cash used by financing activities was $370.9 million
during 2022, as compared to $697.4 million used during 2021. The decrease in
cash used by financing activities was due to a $432.0 million increase in
borrowings under our Credit Facility, partially offset by $72.9 million in
additional repurchases of our common stock in the current period as compared to
the same period in the prior year. Cash was also used to pay off our $75 million
2022 Series A Notes when due and payable on February 14, 2022.

Cash used to repurchase shares of our common stock increased by $72.9 million
during 2022, as compared to 2021. We believe that the repurchase of our common
stock is a favorable means of returning value to our stockholders and we also
repurchase our stock to offset the dilutive effect of our share-based
compensation programs. Repurchases of our common stock may vary depending upon
the level of other investing activities and the share price. We primarily fund
our share repurchases with cash generated from operations, as well as from
various capital market activities, including the committed available financing
through our Credit Facility. Refer to "Part II, Item 8. Financial Statements and
Supplementary Data, Note 20. Repurchases of Common Stock" to the consolidated
financial statements included in this Annual Report on Form 10-K for additional
information about our share repurchases.

Under the $1.25 billion Credit Facility, the $1.0 billion unsecured credit line
matures on December 9, 2026 and requires no scheduled prepayments before that
date. On October 20, 2022, pursuant to the terms of the Credit Facility, the
term lenders thereunder provided us, as borrower, an incremental term loan in an
aggregate principal amount of $250 million (the "Term Loan"). The Term Loan
matures on October 20, 2025. The net proceeds of the Term Loan were used to
repay previously incurred revolver borrowings under the Credit Facility. The
Term Loan is subject to the same affirmative and negative covenants and events
of default as the borrowings previously incurred pursuant to the Credit
Facility. The applicable interest rate for the Term Loan is consistent with our
line of credit, and is calculated at a per annum rate equal to either (at our
option) (1) a prime rate plus a margin ranging from 0.0{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} to 0.375{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} based on our
consolidated leverage ratio, (2) an adjusted term SOFR rate, plus 0.10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}, plus a
margin ranging from 0.875{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} to 1.375{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} based on our consolidated leverage ratio,
or (3) an adjusted daily simple SOFR rate, plus 0.10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}, plus a margin ranging
from 0.875{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} to 1.375{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} based on our consolidated leverage ratio. Refer to "Part
II, Item 8. Financial Statements and Supplementary Data, Note 13, Debt" for
additional information about our applicable interest rates on our Credit
Facility. Under the Credit Facility, we also pay quarterly commitment fees
ranging from 0.075{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} to 0.25{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc}, based on our leverage ratio, on any unused
commitment.

Under the Credit Facility, the net repayment and borrowing activity resulted in
increased cash used of $432.0 million during 2022, as compared to 2021. At
December 31, 2022, we had $329.0 million outstanding on our line of credit and a
$250.0 million Term Loan, for a total of $579 million outstanding under the
Credit Facility. At December 31, 2021, we had $73.5 million in outstanding under
the Credit Facility. The general availability of funds under the Credit Facility
was further reduced by $1.5 million for letters of credit that were issued
primarily in connection with our workers' compensation policy at December 31,
2022 and $1.4 million at December 31, 2021. The Credit Facility contains
affirmative, negative, and financial covenants customary for financings of this
type. The negative covenants include restrictions on liens, indebtedness of
subsidiaries of the Company, fundamental changes, investments, transactions with
affiliates, and certain restrictive agreements and violations of laws and
regulations. The financial covenant is a consolidated leverage ratio test that
requires our ratio of debt to earnings before interest, taxes, depreciation,
amortization, and share-based compensation not to exceed 3.5-to-1. At December
31, 2022, we were in compliance with the covenants of the Credit Facility. The
obligations under the Credit Facility may be accelerated upon the occurrence of
an event of default under the Credit Facility, which includes customary events
of default including payment defaults, defaults in the performance of the
affirmative, negative and financial covenants, the inaccuracy of representations
or warranties, bankruptcy and insolvency related defaults, defaults relating to
judgments, certain events related to employee pension benefit plans under the
Employee Retirement Income Security Act of 1974, ("ERISA"), the failure to pay
specified indebtedness, cross-acceleration to specified indebtedness and a
change of control default.

In February 2022, we paid off our $75 million 2022 Series A Notes with cash
provided by operations and financing activity. On July 21, 2021, we repaid our
$50 million 2021 Series A Notes in full with cash provided by operations. The
aggregate principal amounts of our 2023 Series A Notes for $75 million will
become due and payable on December 11, 2023. We anticipate paying off our 2023
Series A Notes when due with cash provided by borrowings under our Credit
Facility and cash provided by operations. Should we elect to prepay any of our
senior notes, such aggregate prepayment will include the applicable make-whole
amount(s), as defined within the applicable Senior Note Agreements.
Additionally, in the event of a change in control of the Company or upon the
disposition of certain assets of the Company, the proceeds of which are not
reinvested (as defined in the Senior Note Agreements), we may be required to
prepay all or a portion of the senior notes.

The obligations under the senior notes may be accelerated upon the occurrence of
an event of default under the applicable Senior Note Agreements, each of which
includes customary events of default including payment defaults, defaults in the
performance of the affirmative, negative and financial covenants, the inaccuracy
of representations or warranties,
                                       53
--------------------------------------------------------------------------------

bankruptcy and insolvency-related defaults, defaults relating to judgments,
certain events related to employee pension benefit plans under ERISA, the
failure to pay specified indebtedness, and cross-acceleration to specified
indebtedness.


Refer to "Part II, Item 8. Financial Statements and Supplementary Data, Note 13,
Debt" for additional information about our Credit Facility, Senior Notes, and
Senior Note Agreements.

Effect of currency translation on cash. The net effect of changes in foreign
currency exchange rates are related to changes in exchange rates between the
U.S. dollar and the functional currencies of our foreign subsidiaries. These
changes will fluctuate each year as the value of the U.S. dollar relative to the
value of the foreign currencies change. The value of a currency depends on many
factors, including interest rates, and the issuing governments' debt levels and
strength of economy.

Off-Balance Sheet Arrangements. We have no off-balance sheet arrangements or
variable interest entities except for letters of credit and third-party
guarantees, as reflected in "Part II, Item 8. Financial Statements and
Supplementary Data, Note 13 Debt" and "Part II, Item 8. Financial Statements and
Supplementary Data. Note 16. Commitments, Contingencies and Guarantees" to the
consolidated financial statements for the year ended December 31, 2022, included
in this Annual Report on Form 10-K, respectively.

Financial Covenant. The financial covenant is a consolidated leverage ratio test
that requires our ratio of debt to earnings before interest, taxes,
depreciation, amortization, and share-based compensation, as defined in the
Senior Note Agreements and Credit Facility, not to exceed 3.5-to-1. At December
31, 2022, we were in compliance with the covenants of the Senior Note
Agreements. The following details our consolidated leverage ratio calculation:

(in thousands)                                              Twelve months 

ended

Trailing 12 Months Adjusted EBITDA:                           December 31, 

2022


Net income attributable to stockholders                  $            679,089
Interest expense                                                       39,858
Provision for income taxes                                            180,883
Depreciation and amortization                                         111,900
Acquisition-related expense                                               873
Share-based compensation expense                                       

49,770

Extraordinary and other non-recurring non-cash charges                      -
Adjusted EBITDA                                          $          1,062,373


(dollars in thousands)                                      Twelve months ended
Debt to Adjusted EBITDA Ratio:                                December 31, 

2022


Line of credit                                           $            

579,000

Current and long-term portion of long-term debt                       

769,369

Total debt                                                          

1,348,369

Acquisition-related consideration payable                               3,453
Financing leases                                                            5
Deferred financing costs                                                  407
Gross debt                                               $          1,352,234
Gross debt to Adjusted EBITDA ratio                                      1.27

Cash and cash equivalents                                $           (112,546)
Net debt                                                 $          1,239,688
Net debt to Adjusted EBITDA ratio                                        1.17





                                       54
--------------------------------------------------------------------------------

Commitments, Contingencies and Guarantees


For more information regarding our commitments, contingencies and guarantees,
refer to "Part II, Item 8. Financial Statements and Supplementary Data, Note 16.
Commitments, Contingencies and Guarantees."

For more information on our future lease payments, refer to "Part II, Item 8.
Financial Statements and Supplementary Data, Note 8. Leases" for our minimum
lease payment schedule. The expected timing of payments of our leases may be
different in future years, depending on decisions to extend lease terms and/or
enter into additional leases in the preceding years.

As of December 31, 2022, current liabilities include $579.0 million outstanding
borrowing on our Credit Facility and the current portion of long-term debt of
$75.0 million recorded as current liabilities. Refer to "Part II, Item 8.
Financial Statements and Supplementary Data, Note 13. Debt for more information
about our Credit Facility and for more information on our repayment of our
Senior Notes.

We also have purchase obligations that include agreements and purchase orders to
purchase goods or services that are contractually enforceable and that specify
all significant terms, including fixed or minimum quantities, pricing, and
approximate timing of purchases. As of December 31, 2022, we had approximately
$232.4 million in purchase obligations due in 2023. Our purchase obligations
beyond 2023 are approximately $50.4 million. These purchase obligation amounts
do not include amounts recorded in accounts payable as of December 31, 2022. The
expected timing of payments of our purchase obligations is estimated based on
current information. Timing of payments and actual amounts paid may be
different, depending on the time of receipt of goods or services, or changes to
agreed-upon amounts for some obligations.

Additionally, we have agreements with third parties that we have entered into in
the ordinary course of business under which we are obligated to indemnify such
third parties for and against various risks and losses. The precise terms of
such indemnities vary with the nature of the agreement. In many cases, we limit
the maximum amount of our indemnification obligations, but in some cases those
obligations may be theoretically unlimited. We have not incurred material
expenses in discharging any of these indemnification obligations and, based on
our analysis of the nature of the risks involved, we believe that the fair value
of these agreements is minimal. Accordingly, we did not record any liabilities
for these obligations at December 31, 2022 and 2021, and do not anticipate any
future payments for these guarantees.

As of December 31, 2022, our remaining obligation associated with the
deemed repatriation tax resulting from the Tax Cut and Jobs Act of 2017 is $27.0
million. Our prior overpayments continued to satisfy our installment obligations
through 2022. In 2023, our installment obligation will exceed our remaining
overpayment and we will be required to remit the balance due on the installment.
Our final installment will be paid in 2025. For information on our unrecognized
tax benefits, refer to "Part II, Item 8. Financial Statements and Supplementary
Data, Note 14. Income Taxes."

During the first quarter of 2023, we paid the $15.0 million milestone payment
associated with an arrangement to license intellectual property, which was
expensed in 2022.

                                       55

——————————————————————————–

© Edgar Online, source Glimpses

Family of Damar Hamlin shares update on condition, thanks health care staff

Family of Damar Hamlin shares update on condition, thanks health care staff

>> THIS IS WLWT News 5 Primary THE WAY. >> I Had Never Heard A STADIUM SO SILENT. Expenditures Followers AND CINCINNATI’S Lovers Came Jointly AND OUR HEARTS GOES OUT TO ALL OF THE Players. IT WAS Rough. KELLY: THE Assist IS CONTINUING TO POUR IN Just after DAMAR HAMLIN COLLAPSED AT PAYCOR STADIUM ON THE Field. THANK YOU FOR Becoming a member of US. STEVEN: THE Team States THAT HAMLIN Experienced A CARDIAC ARREST Before THE Game WAS SUSPENDED. FROM THE STADIUM TO THE Healthcare facility FRAN — Supporters AND TEAMMATES HAVE SHARED THEIR PRAYERS. KELLY: WE ARE Leading THE WAY WITH THE Response. WE Start WITH THE Latest ON HIS Situation FROM JOHN LONDON WHO IS Are living AT UC Healthcare Center Where by HAMLIN IS Remaining Handled. JOHN: Yes. I CAN Tell YOU THAT By ALL OF THIS Morning AND INTO Midday, IT IS Quite Considerably LIKE Very last Night. A Worry SOME AND AGONIZING Wait FOR INSERT — FOR Information and facts ON Regardless of whether HIS Ailment IS Strengthening. All those THAT — All those IN Cost Convey to US THAT THEY HAVE NO Indication THAT THERE WILL BE AN UPDATE Whenever Soon. THAT COULD Modify IN AN Fast JUST AS IT COULD Continue to be THE Scenario Through THE Working day AND Past. Very last Formal UPDATE WAS ABOUT 2:00 A.M. INDICATING THAT THE Security WAS SEDATED AND IN Important Issue. Community AND National MEDIA REMAINED CAMPED OUT WITH SOME Enthusiasts THAT HAVE Arrive BY PERIODICALLY TO PAUSE AT THE Front OF THE Clinic Like THIS WEST VIRGINIA Dad WHO Obtained TICKETS FOR HIS SON FOR Christmas, HIS Very first NFL Game, Displaying A Worry SHARED All over THE Group. >> AS A great deal AS WE Preferred TO View Fantastic Soccer, IT WOULD NOT HAVE BEEN — THIS IS Larger THAN THAT. THAT IS ME. I AM PRAYING FOR HIM, THE TEAMMATES, AND Family members AND Every person Included. THE A single Detail I WILL SAY IS ALL SIDES Final Night, YOU KNOW Fans AND Each Groups AND Organizations Ended up Quite Stylish AND Leading-NOTCH. >> I AM NOT Talking TO YOU Fellas, NOT — BUT TO HIM, TO THE LORD. THAT IS Much more Crucial TO Speaking — THEN Talking TO A Digicam. I COULD NOT DO THAT, Without having Saying MY CONDOLENCES OR PRAYERS AND I Had TO BE Listed here. I WOULD NOT HAVE BEEN Able TO Vacation BUT I WOULD’VE JUST Second-GUESSED. IT IS THE Ideal Matter TO DO. WE Stick WITH OUR Fellas. JOHN: IT Definitely WAS A Surprised AND EERIE INVOLVEMENT — Atmosphere Previous Evening AT PAYCOR STADIUM AND AN Anxious Environment Outdoors. THE MEDIA IS HOPING A thing ENCOURAGING WILL Appear TO REPORT Sometime Nowadays, BUT Practically nothing Still. REPORTING Reside, JOHN LONDON. KELLY: WE Received A Assertion FROM THE Relatives. THEY Place A Public Assertion OUT EXPRESSING GRATITUDE FOR THE Like AND Support. “WE ARE DEEPLY MOVED BY THE PRAYERS, Kind Words and phrases, AND DONATIONS FROM Admirers All over THE Region. WE ALSO WANT TO Accept THE Devoted Initially RESPONDERS AND Well being Care Pros AT THE College OF CINCINNATI Medical Middle HAVE Delivered Remarkable Care.” THAT IS THE Hottest WE ARE Finding IN THE Very first TIME WE ARE Hearing FROM THEM Directly. STEVEN: THAT IS Something THA

‘He experienced to be resuscitated twice’: Damar Hamlin’s household shares update, many thanks health and fitness treatment workers

The relatives of Damar Hamlin is thanking initially responders, health and fitness treatment staff members, the crew and admirers for their assistance for Hamlin soon after he endured a cardiac arrest throughout Monday’s match towards the Bengals.”On behalf of our loved ones, we want to categorical our sincere gratitude for the enjoy and support revealed to Damar during this tough time. We are deeply moved by the prayers, variety terms, and donations from lovers all over the country,” the loved ones reported in a assertion offered by Hamlin’s agent and mate, Jordon Rooney.The Hamlin household went on to thank initial responders and the staff members at UC Health care Heart for furnishing excellent treatment to Hamlin.”We really feel so blessed to be part of the Buffalo Payments firm and to have their guidance. We also want to thank Coach Taylor and the Bengals for everything they’ve carried out. Your generosity and compassion necessarily mean the environment to us. Please continue to keep Damar in your prayers. We will launch updates as we have them,” the household mentioned in the statement. The Buffalo Expenditures produced a statement indicating Hamlin experienced a cardiac arrest right after earning a tackle for the duration of Monday’s sport. The team claims Hamlin’s heartbeat was restored on the field, and he was transferred to the UC Professional medical Heart for even further tests and remedy. He is presently sedated and outlined in essential condition, the group claimed. Hamlin’s uncle Dorrian Glenn spoke with CNN outside the house of UC Healthcare Centre on Tuesday night.Glenn claimed as his relatives was watching the sport in Pittsburgh, they just understood Hamlin was heading to get back again up. “We were being in Pittsburgh watching it on Television set and his minimal brother was there with us and when he observed his brother drop like that and when I inform you I have never ever witnessed him cry or scream like that, like we were being making an attempt to calm him down, like it’s all right you know he’s gonna get again up, the subsequent thing you know it is 10 minutes later they’re accomplishing upper body compressions, it really is a 50 percent hour afterwards they’re however not actively playing, ” Glenn stated. “Like my nephew in essence died on the discipline and they introduced him again to lifetime. I mean that is just heartbreaking…it just it genuinely was a intestine punch person.” Glenn reported Hamlin experienced to be resuscitated 2 times, once on the discipline and again when he arrived at UC Professional medical Center. In accordance to Glenn, Hamlin is now “flipped above on his stomach” in the medical center to support with the blood on his lungs. “Medical professionals claimed that Hamlin is on his belly to enable acquire the strain of the lungs, so they don’t have to operate as really hard,” Glenn said. Glenn went on to say that the following action is to get Hamlin, who is even now sedated on a ventilator, to breathe on his individual.Fans, athletes and public figures have been sharing messages of help along with prayers, many have donated to Hamlin’s toy generate charity, boosting thousands and thousands in a make any difference of hrs.

The family of Damar Hamlin is thanking 1st responders, wellbeing care personnel, the crew and lovers for their assist for Hamlin soon after he suffered a cardiac arrest all through Monday’s match versus the Bengals.

“On behalf of our loved ones, we want to convey our honest gratitude for the adore and help shown to Damar during this complicated time. We are deeply moved by the prayers, form words, and donations from admirers about the nation,” the household claimed in a statement provided by Hamlin’s agent and buddy, Jordon Rooney.

The Hamlin spouse and children went on to thank first responders and the staff members at UC Healthcare Center for furnishing fantastic treatment to Hamlin.

“We truly feel so blessed to be aspect of the Buffalo Expenses organization and to have their aid. We also want to thank Coach Taylor and the Bengals for almost everything they’ve finished. Your generosity and compassion imply the globe to us. Be sure to retain Damar in your prayers. We will launch updates as we have them,” the family members explained in the statement.

The Buffalo Costs released a assertion stating Hamlin experienced a cardiac arrest immediately after earning a tackle all through Monday’s match. The crew says Hamlin’s heartbeat was restored on the subject, and he was transferred to the UC Healthcare Centre for further more tests and remedy. He is currently sedated and detailed in crucial ailment, the group reported.

Hamlin’s uncle Dorrian Glenn spoke with CNN outdoors of UC Medical Centre on Tuesday night.

Glenn stated as his family was looking at the sport in Pittsburgh, they just realized Hamlin was going to get back up.

“We had been in Pittsburgh watching it on Television and his small brother was there with us and when he noticed his brother drop like that and when I convey to you I’ve by no means seen him cry or scream like that, like we were being making an attempt to quiet him down, like it can be ok you know he’s gonna get again up, the future thing you know it is really ten minutes later on they’re performing chest compressions, it really is a half hour later on they’re still not enjoying, ” Glenn stated. “Like my nephew mainly died on the field and they introduced him again to existence. I necessarily mean that is just heartbreaking…it just it actually was a gut punch man.”

Glenn stated Hamlin had to be resuscitated two times, as soon as on the discipline and once more when he arrived at UC Health care Middle.

In accordance to Glenn, Hamlin is now “flipped around on his stomach” in the healthcare facility to aid with the blood on his lungs.

“Medical doctors mentioned that Hamlin is on his tummy to enable consider the pressure of the lungs, so they don’t have to perform as hard,” Glenn mentioned.

Glenn went on to say that the future move is to get Hamlin, who is even now sedated on a ventilator, to breathe on his very own.

Admirers, athletes and community figures have been sharing messages of aid alongside with prayers, a lot of have donated to Hamlin’s toy drive charity, boosting hundreds of thousands in a make a difference of several hours.

The Pogues’ Shane MacGowan shares health update with fans in video as he confirms serious condition

The Pogues’ Shane MacGowan shares health update with fans in video as he confirms serious condition

Shane MacGowan has shared a overall health update with admirers, right after returning residence from healthcare facility in time for Christmas.

The Pogues frontman, 65, took to his Twitter on New Year’s Eve to share his well-needs and expose he was struggling from a serious problem.

It arrives after Shane arrived back house before this month after shelling out time in hospital battling an infection, noted to be each shingles and encephalitis.

The Pogues’ Shane MacGowan shares health update with fans in video as he confirms serious condition

Update: Shane MacGowan has shared a well being update with lovers, following returning property from hospital in time for Christmas

Encephalitis is an unusual but critical condition in which the mind gets inflamed (swollen).

It can be daily life-threatening and demands urgent treatment method in hospital.

In the video clip, Shane confirmed: ‘Hi good friends, I’m sitting listed here suffering from encephalitis. 

Putting on a pair of sunglasses to protect against the light sensitivity, he extra: ‘The light-weight is killing me […] but I desired to would like you a Happy New Yr and Happy Christmas.

And many more, and all the luck in the world and all the really like. Content Xmas and Delighted New Year, adore Shane.’

Happy New Year! The Pogues frontman, 65, took to his Twitter on New Year's Eve to share his well-wishes

Satisfied New Calendar year! The Pogues frontman, 65, took to his Twitter on New Year’s Eve to share his properly-needs

WHAT IS ENCEPHALITIS?

Encephalitis is an unusual but really serious ailment in which the mind becomes inflamed (swollen).

It can be life-threatening and necessitates urgent cure in clinic.

Anyone can be affected, but the extremely young and pretty aged are most at danger.

Encephalitis in some cases starts off off with flu-like signs, this sort of as a high temperature and headache, but these really don’t generally come about.

A lot more significant indications establish more than hours, times or months, including: confusion or disorientation, seizures (suits), variations in individuality and conduct or reduction of consciousness.

Dial 999 for an ambulance immediately if you or an individual else has these extra significant symptoms. 

It is really not normally apparent what brings about encephalitis, but it can be induced by viral bacterial infections. Various frequent viruses can spread to the mind and lead to encephalitis in rare scenarios, which includes the herpes simplex virus (which triggers chilly sores and genital herpes) and the chickenpox virus.

Source: NHS 

It comes following Shane wished his followers properly around the festive interval on Xmas Day.

He shared a quick snippet of himself waving at the digicam and stating: ‘Merry Christmas everyone’.

Together with the video, he wrote on Twitter: ‘Happy Christmas everybody and thank you for all your messages and prayers’.

Enthusiasts have been still left worried when he was rushed to hospital but his spouse Victoria Mary Clarke verified on December 15 that he was back home.

Composing to her followers on Twitter, Irish journalist Victoria, 56, wrote: ‘Shane is house and we are likely to look at the football ⚽️!

‘Thank you every person who has been messaging and blessings to everyone who has a cherished a single in hospital and who is in clinic themselves and blessings to the medical professionals and nurses! @ShaneMacGowan.’

Shane was wrapped up warm in the image shared to her 29,000 followers, carrying a fluffy hat, sunglasses and included in a blanket.

Shane, who has used a wheelchair since he broke his pelvis in 2015, has been in and out of hospital in the latest decades. 

Lovers wished the singer, whose hits involve Fairytale of New York, a fast restoration and hoped he’d be home for Xmas.

The singer’s return household implies he will be equipped to enjoy his 65th birthday – which is on Christmas Working day. 

Victoria previously up to date his lovers with a picture of the musician smiling from his hospital mattress.

Alongside the snap, she wrote: ‘Fingers crossed @ShaneMacGowan will be house tomorrow! @PoguesOfficial.

Victoria gave lovers an update on her husband’s wellness previously this month, tweeting that ‘doctors are assured he will be Ok.’ 

‘I just preferred to thank everybody who has been sending good needs for @ShaneMacGowan, he is currently being taken care of for an an infection and the doctors are assured that he will be ok.’

‘I am just unbelievably grateful to them and to all of you,’ Victoria wrote. 

Victoria shared a photo of the musician smiling as she uncovered he had been admitted to medical center. 

Festive: He shared a short snippet of himself waving at the camera and saying: 'Merry Christmas everyone'

Festive: He shared a shorter snippet of himself waving at the digicam and stating: ‘Merry Christmas everyone’

She tweeted: ‘Please deliver prayers and healing vibes to Shane MacGowan in hospital once again and seriously hoping to get out asap!! Thank you.’

1 enthusiast wrote beneath her update: ‘Not at Xmas, the man is the sound of Christmas… I hope he recovers swiftly and not also a great deal irritation.’

Victoria advised the Irish Mirror that Shane is finding it ‘frustrating’ and would like to get out immediately after currently being admitted.

Health: The Pogues frontman was rushed to hospital earlier this month where he was being 'treated for an infection' (pictured with his wife Victoria)

Wellbeing: The Pogues frontman was rushed to hospital previously this month where by he was getting ‘treated for an infection’ (pictured with his spouse Victoria)

She stated: ‘I’m unquestionably hoping he gets out this week. He’s a little bit pissed off, I believe. He finds it really frustrating… he wishes to get out.’

The few have been alongside one another for extra than 35 years and tied the knot at Copenhagen City Hall in Denmark in November 2018.

The personal ceremony was attended by their shut good friend Johnny Depp, who performed. 

Hospitalised: Shane, who has used a wheelchair since he broke his pelvis in 2015, has been in and out of hospital in recent years

Hospitalised: Shane, who has utilized a wheelchair given that he broke his pelvis in 2015, has been in and out of clinic in latest a long time

Recovering: Victoria gave fans a recent update on her husband's health, tweeting that 'doctors are confident he will be OK'

Recovering: Victoria gave admirers a new update on her husband’s well being, tweeting that ‘doctors are confident he will be OK’

The Irish singer-songwriter has had health troubles considering that he broke his pelvis. 

In 2021 he fell and broke a knee, just before tearing ligaments in his still left knee, in no way thoroughly recovering from the accidents.

In April he confirmed that he ‘can’t wander any more’.

Wife: Victoria, who married Shane in an intimate ceremony in Copenhagen in 2018 (pictured), asked fans to pray for him earlier this month

Wife: Victoria, who married Shane in an personal ceremony in Copenhagen in 2018 (pictured), questioned lovers to pray for him before this thirty day period

He has also been open about his battle with dependancy and in 2015 had to get a comprehensive set of enamel implants after a long time of consuming and drugs ruined his authentic kinds.

But just previous week he seemed in good spirits when he delighted enthusiasts by joining TikTok, clocking up 840,000 sights for his to start with online video.

He explained in the 17-2nd clip: ‘Welcome to Shane MacGowan on TikTok, I hope you love. God bless, Shane.’ 

Health scare: Taking to Twitter Victoria shared a picture of Shane smiling and told fans he was back in hospital

Well being scare: Getting to Twitter Victoria shared a image of Shane smiling and informed fans he was again in hospital

Benedict XVI news: Vatican gives update on former Pope’s condition

Benedict XVI news: Vatican gives update on former Pope’s condition

Pope Francis asks for prayers for ‘very sick’ predecessor Pope Benedict XVI

The Vatican has said former Pope Benedict’s condition remains “grave” but stable, after Pope Francis said the former pontiff is “very ill”.

“The Pope Emeritus managed to rest well during the night, he is absolutely lucid and aware, and today, even though his condition remains grave, the situation is at the moment stable,” Vatican spokesman Matteo Bruni said.

The Vatican previously said that the deterioration in his health was due to his “advanced age” and added that Benedict was being constantly monitored by doctors.

Pope Francis had said on Wednesday: “I would like to ask all of you for a special prayer for Pope Emeritus Benedict, who, in silence, is sustaining the Church. Let us remember him.

“He is very sick, asking the Lord to console and sustain him in this witness of love for the Church, until the end.”

The latest statement did not provide any specifics about Benedict’s condition, but Francis repeated a call for prayer to “accompany” Benedict “in these difficult hours”

Benedict, who is 95, became the first pope in some 600 years to resign in 2013. He has been living in the Vatican since then.

1672352676

Who is former pope Benedict XVI

Former pope Benedict, who Pope Francis said on Wednesday was “very sick”, resigned in 2013, the first pontiff in 600 years to take such a step rather than rule for life.

For nearly 25 years, the former pope, then known as Cardinal Joseph Ratzinger, was the powerful head of the Vatican’s doctrinal office, the Congregation for the Doctrine of the Faith (CDF). As a theological conservative, Mr Ratzinger left Germany and his post as archbishop of Munich in 1982 to head the CDF.

His disciplining of Latin American priests who promoted Marxist-influenced Liberation Theology bestowed him with the sobriquet “God’s Rottweiler”.

Maryam Zakir-Hussain29 December 2022 22:24

1672344906

Pope Benedict XVI will be remembered as ‘one of the great theologians of the 20th century’

The Catholic Archbishop of Westminster has said that Pope Emeritus Benedict XVI will be remembered as “one of the great theologians of the 20th century”, as the 95-year-old former pontiff’s health worsens.

Speaking on Times Radio, Cardinal Vincent Nichols said: “I met Pope Benedict on quite a number of occasions, and he was a very sensitive, a very thoughtful person, who was a great theologian.

“He will be remembered as one of the great theologians of the 20th century.

“But he was always so courteous. When he came to this country in 2011 he was described as ‘God’s Rottweiler’, but by the time he left I think he was considered to be everybody’s great uncle.

“There was a real gentleness about him, and when I saw him just over a year ago, September last year, that hadn’t changed. He was very very weak, but very bright and very alert and very with it.

“It’s not surprising that his life would appear to be coming to an end, he is 95 and he has been poorly for quite a long time.”

Maryam Zakir-Hussain29 December 2022 20:15

1672341306

Watch: Pope Francis asks for prayers for ‘very sick’ predecessor Pope Benedict XVI

Pope Francis asks for prayers for ‘very sick’ predecessor Pope Benedict XVI

Maryam Zakir-Hussain29 December 2022 19:15

1672337706

Pope Benedict’s decision to resign in 2013 will remain ‘an exception’

The Catholic Archbishop of Westminster has said he believes that Pope Emeritus Benedict XVI’s historic decision to resign from his post due to advancing age in 2013 will remain “an exception”.

Speaking on Times Radio, Cardinal Vincent Nichols also described the “great affinity” between the former pope and the late Queen, and his admiration for her continuing royal duties until the end.

On the former pope Benedict resigning his post, he said: “This is the first time in 600 years, so who knows what might develop. I think it will remain an exception myself.

“I think there was a great affinity between Pope Benedict and her Majesty Queen Elizabeth II,” he added.

“When Benedict decided to come to this country, he decided that the first thing he had to do was visit the Queen. And she was 95, she held her office to the end and I think he admired that very much.

“It was a measure of his self-understanding and the difficulties he was getting into physically as well that he said no, it needs somebody else to do this.”

Pope Emeritus Benedict XVI shared a ‘great affinity’ with the late Queen, the Catholic Archbishop of Westminster has said

(PA)

Maryam Zakir-Hussain29 December 2022 18:15

1672333337

The faithful in Benedict’s native Bavaria pray for his health

People in Pope Benedict XVI’s Bavarian homeland prayed Thursday for the retired pontiff, a favorite son of the region even 40 years after he left Germany for the Vatican and nearly a decade after his resignation stunned the world.

At the St. Oswald church in the small town of Marktl am Inn, where a future pope named Joseph Ratzinger was baptized more than 95 years ago, Sandra Maier, the lay head of the local congregation, put up a framed picture of Benedict, lit a red candle and arranged a small pew so parishioners could kneel and pray for him.

Maier, who was also baptized at the church, said she was “shaken and deeply moved by the news” from the Vatican on Wednesday that Benedict’s health had deteriorated. “I wish for him to have an easy time now and not suffer so much,” she said.

“We are proud here in Marktl that we have a Bavarian pope,” Maier, 50, said, recalling the two times she met him personally. “He’s a good man and was a great pope”

The German Catholic Church’s leadership called for prayers for Benedict after the Vatican’s announcement. “Pope Benedict XVI has prayed for us these many years; now let us pray for him,” said Bishop Rudolf Voderholzer of Regensburg, a city where Ratzinger taught at the university in the 1970s.

Bishop Stefan Oster of Passau, the diocese where Marktl is located, said Benedict was alert but physically very weak when he saw him in November. “If he is now getting even weaker, it is easy to imagine that he is on the last stretch of his earthly way,” Oster said. “Please all accompany him in prayers.”

(AFP via Getty Images)

Holly Bancroft29 December 2022 17:02

1672330720

Vatican: Benedict XVI is lucid and stable, but his condition is ‘serious’

The Vatican said Thursday that Pope Emeritus Benedict XVI was lucid, conscious and stable, but that his condition remains serious a day after officials revealed that the 95-year-old’s health had deteriorated recently.

A statement from Vatican spokesman Matteo Bruni said Pope Francis asks for continued prayers “to accompany him in these difficult hours.”

Read the full story here:

Holly Bancroft29 December 2022 16:18

1672326737

Who is former pope Benedict XVI?

Former pope Benedict, who Pope Francis said on Wednesday was “very sick”, resigned in 2013, the first pontiff in 600 years to take such a step rather than rule for life.

For nearly 25 years, the former pope, then known as Cardinal Joseph Ratzinger, was the powerful head of the Vatican’s doctrinal office, the Congregation for the Doctrine of the Faith (CDF). As a theological conservative, Mr Ratzinger left Germany and his post as archbishop of Munich in 1982 to head the CDF. His disciplining of Latin American priests who promoted Marxist-influenced Liberation Theology bestowed him with the sobriquet “God’s Rottweiler”.

Despite his reputation as a hardliner, his eight-year papacy was marked by missteps and scandal. He admitted a “lack of resolve in governing and decision taking.”

Read our profile of Pope Benedict from reporter Thomas Kingsley here:

Holly Bancroft29 December 2022 15:12

1672322428

Benedict’s condition is ‘grave but stable’, says Vatican

Former Pope Benedict’s condition remains “grave” but stable, the Vatican has said – adding in a statement that he had rested well during the night and was lucid and aware.

“The Pope Emeritus managed to rest well during the night, he is absolutely lucid and aware, and today, even though his condition remains grave, the situation is at the moment stable,” Vatican spokesman Matteo Bruni said.

“Pope Francis renews his request to pray for him and to accompany him in these difficult hours,” Bruni said of the 95-year-old former pontiff.

The statement, the second since Francis disclosed on Wednesday that his predecessor was “very sick”, did not provide any specifics about Benedict’s condition.

Chris Stevenson29 December 2022 14:00

1672321312

Cardinals pray for Pope Benedict

Cardinals from around the world have joined in prayer for Pope Benedict’s health.

Cardinal Blase Cupich, Archbishop of Chicago, urged believers to ask “for the Lord’s grace to help sustain Pope Benedict as he has sustained the Church through his silent witness.”

Cardinal Timothy Dolan, Archbishop of New York, asked the “Catholic faithful of the Archdiocese of New York” to join with him in prayer.

The Archbishop of Westminster, Cardinal Vincent Nichols prayed that God might “sustain and console him at this time”.

Major Archbishop Sviatoslav Shevchuk called on all those in the Ukrainian Greek Catholic Church to pray for the emeritus Pope.

He said: “The whole Ukrainian Greek Catholic Church wants to unite in prayer around this great witness of our times, thanking him for his silent witness as Pope Emeritus and at the same time remembering and seeking to put into practice his work for the unity of the Church, which was an extraordinary feature of his pontificate.”

Archibishop Shevchuk, who met with Benedict on 10 November, said the Pope was “incredibly lucid, informed and solicitous about the situation in Ukraine, and had assured his prayers for the Ukrainian people.”

Holly Bancroft29 December 2022 13:41

1672317952

Former pope Benedict shared ‘great affinity’ with late Queen, says Cardinal

Pope Emeritus Benedict XVI shared a “great affinity” with the late Queen, the Catholic Archbishop of Westminster has said.

The 95-year-old former pope’s historic decision to resign due to age in 2013 will remain “an exception”, and he admired the Queen for continuing her royal duties until the end, according to Cardinal Vincent Nichols.

His comments came after the Vatican said the former pope’s health has worsened due to his age, and doctors are constantly monitoring his condition.

Read the full story here:

Holly Bancroft29 December 2022 12:45