The Future of Medical Treatment for ALS Patients

The Future of Medical Treatment for ALS Patients

Not long ago, soft robotics has emerged as a promising technological innovation to assist clients with neurodegenerative ailments these kinds of as ALS. Scientists have demonstrated the benefits of making use of tender robotics in medical support by offering manage and power to motor steps. In this review, an exosuit with inflatable balloons and actuators was produced to improve arm toughness in ALS people. This breakthrough could assist ALS clients sustain their independence for extended and boost their high-quality of lifestyle. Going forward, delicate robotics has the possible to revolutionise clinical aid by providing additional personalised and adaptive options to individuals with many circumstances. What is gentle robotics, what did the scientists show, and how could soft robotics be made use of in the long run?

What is gentle robotics?

When we consider about robotics, significant mechanical equipment designed from metal springs come to brain, working with big servo motors to manage distinctive arms and rigid, jerky actions in between diverse positions. For the most section, this is an exact impression to conjure up as the vast majority of contemporary robotics do certainly use substantial servo motors shifting to precise angular positions. Some robotics companies, this sort of as Boston Dynamics, have shown robotics capable of fluid movement, with four-legged robots dancing to audio even though bipedal robots throw applications across platforms and complete backflips. 

Having said that, a new spot of robotics is setting up to arise termed “soft robotics” and presents engineers with many benefits more than conventional robotic systems. As the title indicates, tender robotics are robotic programs crafted all-around delicate technologies, cutting down (or getting rid of) the use of ridged elements. For example, a standard robotic arm could be manufactured from metallic or plastics, but a comfortable robotic arm could be created from inflatable rubber or plastic sheet, with pumped air offering the lifting drive.

At the moment, investigation into soft robotics is however in its infancy due to the reasonably new concept at the rear of them. Some researchers have explored their use in navigating about restricted areas, as an inflated plastic form can conveniently deform and wrap all around sharp objects although carrying surveillance gear this sort of as cameras and microphones. This could be beneficial for infrastructure servicing as well as lookup and rescue functions, but as these kinds of robotic products are continue to in their early days, they keep on to be confined to laboratory circumstances.

Researchers show smooth robotics in ALS patients

Recognising the rewards of gentle robotics, scientists from Harvard John A. Paulson University of Engineering and Utilized Sciences (SEAS) and Massachusetts Standard Clinic (MGH) have not long ago developed a wearable robotic system to assistance sufferers suffering from ALS regain motor control. Amyotrophic lateral sclerosis (ALS), also recognized as Lou Gehrig’sGehrig’s disease, is a neurodegenerative affliction that assaults nerves accountable for motor handle, earning it significantly complicated to go (finally major to paralysis).

To help patients with these motor controls, it’sit’s technically attainable to develop an exosuit that detects intended movement and applies mechanical force that stabilises arms and legs. Having said that, this sort of devices are exceptionally large, loud, and possibly perilous, as trapped body pieces can be crushed by effective motors. Rather, the researchers turned their focus to soft robotics, whereby inflatable balloon actuators placed below the arms can offer further assist and balance. The soft character of the actuators stops harm from crushing or squeezing, and the confined mobility of the actuators prevents ligaments from getting bent significantly further than their abilities.

Walsh Lab, Harvard SEAS

Credit: Walsh Lab, Harvard SEAS

The new technique is first calibrated to person sufferers in excess of a time period of 30 seconds, and right after 15 minutes of teaching, clients were being ready to reveal significant enhancement in their means to decide up objects and position them into a bin. In addition, the procedure is in a position to discover supposed motion when disregarding quick, uncontrollable movement to move the actuator to particularly where it is necessary. 

Nonetheless, the present-day system is only ready to get the job done with ALS people in the early phases, where motor controls are however existing, but later on phases of ALS outcome in complete paralysis. As these, the researchers are discovering the use of mind signals to manage gentle robotic actuators, thereby likely giving movement to those people who are paralysed. 

How could gentle robotics be utilised in the upcoming?

What the scientists demonstrated is just the tip of the iceberg that tender robotics has to provide. The capability to restore motion in all those who have constrained control assists to bring independence to thousands and thousands all-around the planet, and not only does this assist to simplicity health-related assets, but it also cuts down the affect of neurodegenerative circumstances.

But the area of tender robotics presents engineers with considerably extra opportunities. Exosuits driven by soft robotics could assist folks carry far more pounds, carry out arduous perform for more time hours, and maximize efficiency in superior-threat scenarios. For instance, firefighters equipped with exosuits could be presented huge quantities of strength to carry folks from burning properties, change heavy particles from collapsed buildings, and even go vehicles one handily to get to all those trapped within or beneath. 

All round, what the researchers have demonstrated in this article is genuinely remarkable and, hopefully, the initially move in preventing from diseases that impact so numerous life.

Who are the leading innovators in treatment evaluation models for the medical devices industry?

Who are the leading innovators in treatment evaluation models for the medical devices industry?

The medical gadgets sector continues to be a hotbed of innovation, with action pushed by an amplified want for homecare, preventative remedies, early prognosis, lowering patient restoration periods and enhancing outcomes, as nicely as the expanding great importance of systems these types of as device finding out, augmented actuality, 5G, and digitalisation. In the very last 3 a long time alone, there have been around 450,000 patents filed and granted in the clinical gadgets sector, according to GlobalData’s report on Synthetic Intelligence in Professional medical Gadgets: Cure analysis types.

Nevertheless, not all innovations are equal and nor do they stick to a consistent upward trend. Instead, their evolution requires the form of an S-formed curve that reflects their typical lifecycle from early emergence to accelerating adoption, right before finally stabilising and achieving maturity.

Determining wherever a unique innovation is on this journey, specially people that are in the rising and accelerating stages, is critical for understanding their current level of adoption and the very likely long run trajectory and affect they will have.

150+ innovations will condition the medical units business

According to GlobalData’s Technological innovation Foresights, which plots the S-curve for the clinical devices field making use of innovation intensity models developed on about 550,000 patents, there are 150+ innovation places that will condition the future of the field.

Within just the rising innovation phase, AI-assisted radiology, movement artefact examination, and treatment method evaluation types are disruptive systems that are in the early phases of software and must be tracked intently. MRI picture smoothing AI-assisted EHR/EMR, and AI-assisted CT imaging are some of the accelerating innovation regions, the place adoption has been steadily rising. Amid maturing innovation spots are laptop-assisted surgical procedures and 3D endoscopy, which are now properly recognized in the field. 

Innovation S-curve for artificial intelligence in the health-related products business

Treatment analysis models is a key innovation spot in synthetic intelligence

Therapy evaluation types refer to a treatment method approach that is peer-reviewed for efficiency. Synthetic intelligence-primarily based therapy versions allow for health professionals to advocate correct treatment method solutions even though saving time for each doctors and individuals.

GlobalData’s investigation also uncovers the companies at the forefront of each innovation place and assesses the potential attain and effects of their patenting activity throughout distinct purposes and geographies.  In accordance to GlobalData, there are 40+ corporations, spanning technology distributors, founded clinical products organizations, and up-and-coming get started-ups engaged in the progress and application of treatment method analysis versions.

Key gamers in remedy analysis versions – a disruptive innovation in the clinical devices business

‘Application diversity’ actions the selection of distinctive purposes determined for each individual related patent and broadly splits businesses into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the amount of unique nations each appropriate patent is registered in and reflects the breadth of geographic application meant, ranging from ‘global’ to ‘local’.

Smith & Nephew is 1 of the major patent filers in the subject of AI-treatment evaluation products. Some other key patent filers in the discipline include Stryker Corp and Johnson & Johnson.

In phrases of software diversity, Motorika qualified prospects the pack, followed by AlterG and Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung eV. By suggests of geographic get to, Novartis holds the prime situation, followed by Johnson & Johnson and Smith & Nephew in the next and third places, respectively.

The clinical local community is rapidly adopting AI into its processes. AI will be a critical driver in producing therapy analysis designs in the future. It will boost the method of knowledge assortment, leading to a greater utilisation of offered facts for recommending procedure. Treatment analysis types are more and more used to measure the efficiency of remedy pathways, both equally from a scientific point of check out, but also in producing an financial assessment of new therapies. Making use of AI or Deep Mastering techniques will direct to improved clinical results but will also allow wellbeing chiefs to better deploy health and fitness means, specifically in moments when there are elevated budgetary constraints.

To more comprehend the key themes and systems disrupting the medical products market, obtain GlobalData’s latest thematic study report on Health care Products.


A new treatment could restore some mobility in people paralyzed by strokes

A new treatment could restore some mobility in people paralyzed by strokes

Sitting down in an exam space, surrounded by medical practitioners and scientists, Heather Rendulic opened her still left hand for the 1st time given that struggling a sequence of strokes nine yrs earlier when she was in her early 20s.

“It was an astounding feeling for me to be ready to do that all over again,” Rendulic claims. “It’s not a little something I ever imagined was doable.”

But immediately just after a surgically implanted unit sent electrical pulses into her spinal wire, Rendulic could not only open her hand but also showed other marked enhancements in arm mobility, scientists report February 20 in Character Medicine. “We all started out crying,” Marco Capogrosso, a neuroscientist at the University of Pittsburgh, said in a February 15 news convention. “We did not genuinely anticipate this could function as rapidly as that.”

The solution is comparable to that not long ago utilized for sufferers paralyzed by spinal twine accidents (SN: 08/03/22). It signifies a promising new method for restoring voluntary motion to people still left with upper-entire body paralysis next strokes, the workforce says.

A stroke takes place when blood source to elements of the mind is reduce off, generally leading to short-term or extensive-term challenges with motion, speech and eyesight. Stroke is a main, and normally underappreciated, bring about of paralysis in the United States by itself, 5 million people are residing with some variety of motor deficit due to stroke. Though actual physical treatment can provide some advancements, no cure exists to assist these people get back total regulate of their limbs — and their life.

Strokes induce paralysis mainly because the relationship amongst the mind and the spinal cord is damaged the brain tries to explain to the spinal wire to move particular muscle tissue, but the information is muddled.

So, having advantage of procedures by now current for spinal injections of anesthetics, the staff invented an electrical machine that can be placed along the spinal wire to encourage the nerves there. The stimulation “does not hurt by any means,” Rendulic claims. “It feels like a vibration.”

By aligning the electrodes on the system with sensory nerves, “we can improve the activation of muscle tissues that are weakened by the stroke,” Douglas Weber, an engineer and neuroscientist at Carnegie Mellon University in Pittsburgh, mentioned at the information conference. Pulses from these electrodes find to amplify alerts from the brain, so that the sensory nerves reply by activating muscle tissues, restoring voluntary physique command to patients.

Rendulic and the other affected individual in the study both of those showed improvement in mobility tasks, including drawing a spiral, opening a lock and gripping and lifting a soup can although the device was on. Procedure sessions of constant electrical stimulation were held for 4 several hours for each day, five days a week, above 29 days, and the advancements persisted for as very long as four months just after treatment method stopped. This tends to make the scientists optimistic that they can get even much better benefits if the remedy ended up paired with intensive physical schooling, Elvira Pirondini, a neuroscientist at the College of Pittsburgh, mentioned at the news convention.

https://www.youtube.com/view?v=tkWOVH4_uJ8

Soon after a collection of strokes 9 yrs in the past, Heather Rendulic shed the use of her left arm and hand. Now, thanks to an implanted gadget that sends electrical pulses into spinal nerves, she has regained some perform. Below, she feeds herself and sorts blocks although the machine is on, but has issues executing those people jobs when the stimulation is turned off. The implant sends electrical pulses into spinal nerves, circumventing the weakened connection in between the brain and the spinal twine. (Devices on her arm are just for monitoring.)

She and the rest of the workforce are actively screening the system with other people, and also exploring if pairing it with bodily training can make improvements to outcomes. The scientists are hopeful that it will be extensively accessible for the reason that the surgical procedure to implant it is minimally invasive and program, and the worth of the method can be plainly shown, which is important to encourage insurance policy firms to address it.

The procedure may not work properly for sufferers with intense mobility impairment, says UCLA neurologist Bruce Dobkin, who was not involved with the examine. But it could provide as a “new resource to attempt to increase the recovery” of stroke sufferers with more reasonable paralysis, in mixture with other therapies.

For Rendulic, the tested likely of applying spinal wire stimulation to address paralysis brought about by stroke provides her hope for the upcoming. “I actually hope and pray that this gets widely out there,” she claims, “because I know it is likely to alter so several lives.”

A look back at Jimmy Carter’s health journey and thoughts on aging

A look back at Jimmy Carter’s health journey and thoughts on aging

Previous President Jimmy Carter, who is getting hospice treatment at house right after a collection of small medical center stays, has experienced a number of wellbeing concerns in current yrs.

At 98 yrs aged, Carter is the oldest and longest-lived U.S. President, telling Persons Magazine in 2015, when he was 95, that he never envisioned to be alive for as extensive as he has.

In this article are some of the the latest overall health worries that Carter has confronted:

Surgical procedure on his liver

Carter underwent elective surgical procedure on Aug. 2, 2015, at Emory University Hospital to eliminate a little mass in his liver, the Carter Middle introduced at the time.

Even though the medical procedures was effective and medical doctors reported he would make a full restoration, the surgery uncovered further more overall health challenges for the previous president.

2015 most cancers prognosis

On Aug. 11, 2015, Carter said that the surgical procedure on his liver discovered that he had most cancers and it spread to other areas of his system.

“I will be rearranging my plan as essential so I can endure treatment by medical professionals at Emory Health care,” he explained in a statement by way of his corporation.

There is a heritage of most cancers in Carter’s family members. His mother died of breast cancer. His father, two sisters and brother all died of pancreatic cancer.

PHOTO: FILE - Former President Jimmy Carter sits on the Atlanta Falcons bench before the first half of an NFL football game between the Atlanta Falcons and the San Diego Chargers, Oct. 23, 2016, in Atlanta.

Previous President Jimmy Carter sits on the Atlanta Falcons bench before the very first 50 percent of an NFL soccer activity in between the Atlanta Falcons and the San Diego Chargers, Oct. 23, 2016, in Atlanta.

John Bazemore/AP, FILE

Medical practitioners uncovered that Carter had melanoma, 1 of the most typical cancers impacting adult men and girls in the U.S. and the most unsafe kind of pores and skin most cancers.

Melanoma has a very substantial danger of metastasizing through the bloodstream or lymphatic technique and to other body pieces.

The 39th president explained at an Aug. 20, 2015 push convention, that an MRI of his head and neck exposed that the cancer experienced spread to 4 distinct parts of his mind.

Carter, who was 90 several years old at the time, said that when he found out that the cancer had distribute, he imagined he failed to have substantially time left, which didn’t alarm him.

“I just considered I experienced a handful of months still left, but I was amazingly at ease,” Carter explained. “I’ve had a great lifestyle. I have hundreds of friends…so I was surprisingly at relieve, substantially much more so than my spouse was.”

At the push meeting, Carter explained that even with the simplicity of being aware of he lived a comprehensive existence, he would comply with his doctors’ recommendation to be certain he “extends” his life as very long as he can.

He underwent surgical procedure, radiation treatment and most cancers treatment method identified as immunotherapy to battle the disease.

Carter obtained treatment plans amongst August 2015 via February 2016.

In December 2015, responding perfectly to remedy, Carter mentioned MRI scans showed that there were no more time any indications of places of melanoma on his mind, nor did any new ones build.

The previous president announced to his church in March 2016, that physicians stopped his remedy just after looking at no indications of tumors.

According to industry experts, the effective treatment was most likely mainly owing to the drug pembrolizumab, which targets cancer by ramping up the body’s immune procedure. The U.S. Foodstuff and Drug Administration accepted the procedure in 2011.

Dehydration at Habitat for Humanity

On July 13, 2017, the 2002 Nobel Peace Prize recipient was taken to the medical center for observation just after getting to be dehydrated while constructing properties in the incredibly hot solar at a Habitat for Humanity web-site in Winnipeg, Canada.

Carter was back at the function site the following day pursuing his discharge from the hospital, the Carter Middle announced.

PHOTO: FILE - Former President Jimmy Carter smiles as he is awarded the Order of Manuel Amador Guerrero by Panamanian President Juan Carlos Varela during a ceremony at the Carter Center, Jan. 14, 2016, in Atlanta.

Former President Jimmy Carter smiles as he is awarded the Order of Manuel Amador Guerrero by Panamanian President Juan Carlos Varela through a ceremony at the Carter Middle, Jan. 14, 2016, in Atlanta.

John Bazemore/AP, FILE

Falls at his Ga property

Carter fell at his Plains, Ga, home as he was leaving to go turkey searching, breaking his hip, his firm announced in May perhaps 2019.

The Grammy Award winner had hip alternative surgical treatment at Phoebe Sumter Health-related Center in Americus, Ga, on May possibly 13, 2019.

“President Carter said his most important concern is that turkey period ends this week, and he has not achieved his restrict,” the Carter Basis claimed. “He hopes the Point out of Ga will allow for him to rollover the unused limit to next 12 months.”

A few times afterwards, the Carter Heart declared that he would be going through bodily remedy from the medical procedures and recovering at property.

On Oct. 6, 2019, Carter fell at his dwelling in Ga. He finished up finding stitches over one of his eyebrows.

A couple of weeks later on, on Oct. 22, 2019, the former president fell once again at his household. He was admitted to the healthcare facility and taken care of for a minor pelvic fracture, the Carter Centre reported.

Carter experienced medical procedures on Nov. 12, 2019, to reduce force on his brain caused by bleeding because of the falls at his dwelling. According to the Carter Middle, there were not any difficulties from the surgery.

PHOTO: FILE - Former U.S. President Jimmy Carter takes questions from the media during a news conference at the Carter Center in Atlanta, Aug. 20, 2015.

Previous U.S. President Jimmy Carter will take thoughts from the media for the duration of a news meeting at the Carter Centre in Atlanta, Aug. 20, 2015.

John Amis/Reuters, FILE

At-household hospice care

On Saturday, The Carter Center introduced that the former president is acquiring hospice treatment at household, where by he is envisioned to expend his final moments with his cherished types, relatively than seek out more health-related procedure.

“He has the complete assistance of his family members and his clinical group,” the Carter Centre mentioned in a statement. “The Carter relatives asks for privateness during this time and is grateful for the problem demonstrated by his quite a few admirers.”

Regardless of the wellness problems in current decades, Carter credits his relationship to his spouse, former initially lady Rosalynn Carter, for his longevity.

“It’s difficult to reside until you might be 95 several years previous,” he informed Individuals Magazine in 2019, a couple months following his second fall. “I believe the very best rationalization for that is to marry the best husband or wife, anyone who will just take care of you and engage and do things to challenge you and keep you alive and intrigued in lifetime.”

ABC News’ Meredith Deliso, Julia Jacobo, Dr. Chantel Strachan and Gillian Mohney contributed to this report.

Jimmy Carter, 98, in hospice care: Oldest U.S. president spending ‘remaining time’ at home

Jimmy Carter, 98, in hospice care: Oldest U.S. president spending ‘remaining time’ at home

Jimmy Carter, the longest living president in U.S history, has decided to live out his final days in hospice care in his Georgia home with wife Rosalynn by his side rather than seek more medical treatment.

The 98-year-old’s charity The Carter Center announced on Twitter on Saturday that after a series of short hospital stays, the former peanut farmer has ‘decided to spend his remaining time at home with his family and receive hospice care instead of additional medical intervention.’

It said the Democrat, who has dedicated his life to public service and charity, has the full support of his medical team and family – but did not elaborate on what conditions had prompted the recent hospital visits.

His grandson Jason tweeted on Saturday that he visited his grandparents, who have been married for 76 years, and said they ‘are at peace and—as always—their home is full of love’.

Carter, a Navy veteran and Nobel Peace Prize winner, became the 39th U.S. president when he defeated former President Gerald R. Ford in 1976 with the country still reeling after the Watergate scandal under President Richard Nixon.

Jimmy Carter, 98, in hospice care: Oldest U.S. president spending ‘remaining time’ at home

Former US president Jimmy Carter has decided to receive hospice care and ‘spend his remaining time at home with his family’ instead of additional medical intervention, the Carter Center said on Saturday 

He served a single term that was blighted by an oil crisis that forced Americans to wait in line for gas, and was defeated by Republican Ronald Reagan in 1980.

Since then he has committed himself to philanthropy and living a humble life with his wife of 76 years Rosalynn, his four children, grandchildren and great-grandchildren.

In 2019, at the age of 95, he helped build a home in Nashville for one of his beloved charities, Habitat for Humanity.

In August 2015, Carter had a small cancerous mass removed from his liver. The following year, Carter announced that he needed no further treatment, as an experimental drug had eliminated any sign of cancer. 

Carter has been married to his wife, Rosalynn Carter, for over 76 years, the longest marriage of any American president and first lady.

He was born on October 1, 1924, with the rarely used full name James Earl Carter, Jr. and raised during the Great Depression. 

Carter is the son of a Georgia peanut farmer and peanut farming, talk of politics, and devotion to the Baptist faith were said to have been the pillars of his upbringing. 

Her graduated from the Naval Academy in Annapolis, Maryland, in 1946 and married Rosalynn Smith shortly afterward. 

The couple has three sons, John William (Jack), James Earl III (Chip), Donnel Jeffrey (Jeff), and a daughter, Amy Lynn. 

Carter served seven years as a Naval Officer before returning to Georgia, where he entered state politics in 1962. 

Eight years later, he was elected Governor of Georgia. 

He launched a bid for the White House in 1974 and built momentum over the next two years, beating out President Gerald R. Ford. 

While president, he established two new cabinet-level departments: the Department of Energy and the Department of Education. 

He said that he aimed to make government ‘competent and compassionate’. 

By the end of his administration, inflation and interest rates were at near record highs but Carter could still claim an increase of nearly eight million jobs and a decrease in the budget deficit. 

He had also worked on the energy shortage by establishing a national energy policy and by decontrolling domestic petroleum prices to stimulate production.

And he sought to improve the environment, expanding the national park system to include protection of 103 million acres of Alaskan lands.  

Carter pictured here in 2018 with wife Rosalynn, to whom he has been married for 76 years

Carter pictured here in 2018 with wife Rosalynn, to whom he has been married for 76 years

Carter is pictured here in 2018 during the first day of the week-long Jimmy & Rosalynn Carter Work Project

Carter is pictured here in 2018 during the first day of the week-long Jimmy & Rosalynn Carter Work Project

President Jimmy Carter and First Lady Rosalynn Carter dance at a White House Congressional Ball in 1977. The couple celebrated 76 years of marriage earlier this year

President Jimmy Carter and First Lady Rosalynn Carter dance at a White House Congressional Ball in 1977. The couple celebrated 76 years of marriage earlier this year

Carter with his wife Rosalynn and their daughter Amy at the Baptist church in his hometown of Plains, Georgia in 1976

Carter with his wife Rosalynn and their daughter Amy at the Baptist church in his hometown of Plains, Georgia in 1976. Last year, Carter said he could not have managed being President at 80, appearing to take a dig at Joe Biden and Donald Trump’s age ahead of the election

Both during and after his presidency, he became known as an international human rights champion.

Carter was at the forefront of brokering the Camp David Accords between Israeli Prime Minister Menachem Begin and Egyptian President Anwar Sadat in 1978.

He saw the start of the Iran hostage crisis as well as the first efforts toward developing an energy independence policy.

According to VOA, his decision in 1980 to authorize a military rescue of American hostages in Iran contributed to his reelection loss that year.  

Carter was awarded the Nobel Peace Prize in 2002 after he created the Carter Center to promote human rights worldwide.

Jimmy Carter pictured on his peanut farm in Plains, Georgia, in 1976

Jimmy Carter pictured on his peanut farm in Plains, Georgia, in 1976

He has also spent time post-presidency building Habitat for Humanity homes, he nation’s most prominent housing charity, and writing more than two dozen books. 

In 2015, Carter was diagnosed with metastatic melanoma that was detected in his liver and spread to his brain.

About six months after the diagnosis, Carter announced he no longer needed cancer treatment due in part to a groundbreaking medication that trains the immune system to fight cancer tumors.

He was hospitalized two years later for dehydration while building homes with Habitat for Humanity in Canada.

He was back at the work site the next day after he was discharged.

Carter has also traveled the world for elections and worked with the Carter Center to eradicate diseases.

The center began to work toward the eradication of Guinea worm disease in 1986, when 3.5 million people had it. Last year, only 54 did, according to the Atlanta Journal Constitution. 

In Colombia, Ecuador, Mexico and Guatemala, the center established a river blindness eradication program which helped eliminate the disease. 

Despite receding from public view due to health issues, Carter remains a quiet force in politics at home and, through his post-presidential Center, in public health and human rights advocacy around the world.

Though Carter remained neutral in Democrats’ 2020 presidential primary he fielded calls and visits from multiple candidates. 

Jimmy and Rosalynn Carter, now 95, recorded audio addresses for Democrats’ virtual national convention urging the election of nominee Joe Biden, who was a young senator from Delaware when Jimmy Carter won the presidency in 1976.

President Joe Biden and first lady Jill visited Jimmy and Rosalynn Carter at their Plains, Georgia, home in May, 2021

President Joe Biden and first lady Jill visited Jimmy and Rosalynn Carter at their Plains, Georgia, home in May, 2021 

Jimmy Carter waves before the crowd on the floor of the Democratic Convention of 1980

Jimmy Carter waves before the crowd on the floor of the Democratic Convention of 1980

President Ronald Reagan and First Lady Nancy Reagan join Former President Jimmy Carter and Former First Lady Rosalynn Carter at the Carter Center in October 1986

President Ronald Reagan and First Lady Nancy Reagan join Former President Jimmy Carter and Former First Lady Rosalynn Carter at the Carter Center in October 1986 

A World War II veteran, Carter is proud that the U.S. engaged in no foreign wars during his tenure. He is pictured here with his wife (left) and running mate Walter and wife Joan Mondale after accepting the democratic nomination for president at the DNC in New York City in 1977

A World War II veteran, Carter is proud that the U.S. engaged in no foreign wars during his tenure. He is pictured here with his wife (left) and running mate Walter and wife Joan Mondale after accepting the democratic nomination for president at the DNC in New York City in 1977

‘Joe Biden was my first and most effective supporter in the Senate,’ Carter told the convention. ‘For decades, he’s been my loyal and dedicated friend.’

Carter also gained newfound attention upon the death of Supreme Court Justice Ruth Bader Ginsburg. 

Carter is the only president since 1850 not to make a single Supreme Court nomination, but he reshaped the lower courts with a record number of nominations of women and non-white jurists, Ginsburg being the most notable.

In 1980, Carter tapped Ginsburg, then the nation’s most accomplished civil rights attorney, for the U.S. Court of Appeals for the District of Columbia Circuit, considered the nation’s second highest court. 

She was the second woman Carter nominated for the D.C. Circuit, setting her up for a promotion to Supreme Court 13 years later.

‘He looked around at the federal judiciary and he said, `You all look like me, but that’s not how the great United States looks,’ Ginsburg said to a Fordham University Law School forum in 2016.

Pictured in 1976, then-democratic vice presidential candidate Walter Mondale (left) and presidential candidate Jimmy Carter talk to reporters during their campaign in 1976

Pictured in 1976, then-democratic vice presidential candidate Walter Mondale (left) and presidential candidate Jimmy Carter talk to reporters during their campaign in 1976

The former president disclosed that he voted for Bernie Sanders in the 2016 Democratic primary, but didn't back anyone in the 2020 Democratic presidential primaries

The former president disclosed that he voted for Bernie Sanders in the 2016 Democratic primary, but didn’t back anyone in the 2020 Democratic presidential primaries

A WWII veteran, Carter said presidents feed the cycle of going to war, in part because 'we make a hero' out of wartime commanders-in-chief. Pictured meeting with Robert Mugabe

A WWII veteran, Carter said presidents feed the cycle of going to war, in part because ‘we make a hero’ out of wartime commanders-in-chief. Pictured meeting with Robert Mugabe

Perhaps most notable among Carter’s 2020 election maneuvering is the Carter Center for the first time designating the United States as a ‘backsliding’ democracy. 

The Center announced after the Democratic convention that it would devote resources to ensuring free and fair U.S. elections this fall. 

The Carters founded the Center in 1982, two years after he lost his re-election bid to Republican Ronald Reagan.

The Center has monitored more than 110 elections in 39 countries since 1989, but it was a striking development for the institution to turn its focus to Carter’s home country, the world’s leading democratic superpower since World War II. 

Explaining the decision to monitor a U.S. election, a Carter Center statement said ‘backsliding’ democracies are ‘often characterized by polarization, a lack of public trust, ethnic or racial divisions and injustice, and fears that election results won’t be seen as credible or could trigger violence’.

Carter remained neutral in Democrats' 2020 presidential primary he fielded calls and visits from multiple candidates including Pete Buttigieg, pictured, in May 2019

Carter remained neutral in Democrats’ 2020 presidential primary he fielded calls and visits from multiple candidates including Pete Buttigieg, pictured, in May 2019

Carter had cautioned Democrats not to go too far left in the upcoming 2020 election

Carter had cautioned Democrats not to go too far left in the upcoming 2020 election

Siding with Biden over Trump wasn’t surprising for a Democratic former president, but it does involve Carter ignoring one of his own recent observations about the presidency. 

Weeks before his 95th birthday, Carter alluded to the advanced ages of several candidates at the time. 

‘I hope there’s an age limit,’ Carter said jovially at his town hall when asked whether he’d run again. 

Then he turned more serious: ‘If I were just 80 years old, if I was 15 years younger, I don’t believe I could undertake the duties I experienced when I was president.’

Only a handful of former presidents have lived past 90 years, including former President Ronald Reagan, Carter’s successor, who lived to be 93.

America’s founding president, George Washington, was the youngest former president to die – at 57 years and 67 days – in April 1789, nearly three years after he left office.

The announcement comes just a day after a building at the US Naval Academy that had been named after a leader in the Confederate Navy was renamed Friday in honor of former President Carter, who graduated from the academy in 1946.

The decision to rename the engineering building in Annapolis was made after a commission mandated by Congress determined several military assets across all branches of the service had to be renamed because of Confederate ties.

The building that had been called Maury Hall was built and named in the early 1900s after Matthew Fontaine Maury, a naval officer and scientist who joined the Confederates.

The Naval Academy superintendent’s house and a nearby road are named after Franklin Buchanan, the academy’s first superintendent who left to join the Confederate Navy at the start of the Civil War. The academy also is renaming the house and road, but has yet to announce those changes.

Carter did not attend the ceremony, though some of his relatives did.

‘It would be impossible to overstate what this Academy and the Navy has meant to my grandfather, and by extension to my family,’ said Josh Carter, Jimmy Carter´s grandson, in a news release from the Navy.

How eye tests could help detect diabetes, MS, and dementia

How eye tests could help detect diabetes, MS, and dementia

The eyes have long been called the “windows to the soul,” and increasingly, evidence is suggesting that they might be also windows to both the brain and body. Several health conditions can be detected by examination of the eyes, among them diabetes, multiple sclerosis, and even Alzheimer’s disease. Medical News Today spoke to experts in the field to discover how the eye can reveal the body’s secrets.

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How much could our eyes reveal about our health? Image credit: A.J. Schokora/Stocksy.

Most of us have our eyes tested regularly, but few may be aware that an eye test is not just for checking vision and correcting sight problems.

Because it has a “window” at the front, the eye is the only part of the body where doctors can, non-invasively, examine the inside of an organ. At the back of the eye is the retina, where blood vessels and the optic nerve can be clearly seen.

Thanks to this, optometrists and ophthalmologists could diagnose not only disorders of the eye, but also systemic diseases — those that affect other organs in the body or the whole body.

If a routine eye test raises concerns, the optometrist can refer a person to a medical ophthalmologist who will investigate by carrying out further eye examinations. If their investigations reveal a systemic disease, they can then refer the person to the relevant specialist.

Dr. Hagar Ibrahim, senior specialist trainee (ST6) in medical ophthalmology at St. Paul’s Eye Unit, Liverpool University Hospitals NHS Trust, in the United Kingdom, told Medical News Today that “a routine eye examination in which the pupils are dilated using eye drops can provide a full and clear view of the optic nerve, which connects to the brain, the retina, […] and all the blood vessels supplying the retina.”

“Therefore, pathology in the eye can be clearly seen during [an] eye examination, both in localized eye conditions and in systemic disease, truly making the eye a window into the rest of the body,” she added.

“People are often surprised when an eye doctor diagnoses them with a systemic illness but they shouldn’t be. Many people with systemic illnesses are first diagnosed by their eye doctor, which is just one reason why all adults should have regular eye examinations at least every 2 years.”

– Dr. Philip Storey, a board-certified ophthalmologist and fellowship-trained retina specialist at Austin Retina Health

As well as identifying problems with vision, such as nearsightedness, farsightedness, and astigmatism, a routine eye test will detect other eye disorders, such as glaucoma, and age-related macular degeneration.

By examining the blood vessels in the retina and the optic nerve, the optometrist can also discover a lot about a person’s general health.

This non-invasive process can detect many other health conditions that may seem unconnected to the eyes, among them hypertension, diabetes, thyroid disorders, and neurodegenerative diseases such as Alzheimer’s disease, and multiple sclerosis (MS).

“Ocular inflammation can affect many parts of the eye, and can often be the first sign of a systemic disease. The key to diagnosing the cause is in focused history taking followed by [a] guided investigation of the relevant body systems, including blood tests,” explained Dr. Ibrahim.

Changes in the blood vessels in the retina can be early indicators of both diabetes and hypertension.

Dr. Storey told MNT that “[d]iabetes is the most commonly diagnosed disease given the frequency of the illness as well as the classic findings on retina exam, which can include bleeding, leakage of fluid, and areas of poor blood flow.”

Although a firm diagnosis of diabetes can only be made with a blood glucose test, changes in the blood vessels of the retina can give a strong indication that a person may have diabetes. They can then be referred for further testing.

According to the American Academy of Ophthalmology, the signs of diabetic retinopathy can sometimes be detected by eye examination even before a person suspects they may have diabetes.

Once diagnosed, provided the diabetes is well controlled, the person can then minimize the risk of further eye damage, as Dr. Ibrahim explained: “In addition to localized eye therapies such as laser treatment or intravitreal eye injections, improving blood sugar levels by sticking to the proper pharmacological treatment, restricting sugar intake and making necessary lifestyle changes, can result in regression of diabetic retinopathy.”

However, for those with diabetes, the most important eye tests take place after diagnosis, to monitor changes in the eyes and take steps to prevent further damage, as Dr. Howard R. Krauss, surgical neuro-ophthalmologist and director of Pacific Neuroscience Institute’s Eye, Ear & Skull Base Center at Providence Saint John’s Health Center in Santa Monica, CA, noted:

“In most cases, diabetes is diagnosed before changes become evident in the retina, but the retinal examination is a vital part of routine diabetic evaluations, so as to aid in the management of the disease, and to intervene when indicated, with any of a variety of treatments to reduce the risk of blindness from diabetic retinopathy.”

Studies have shown that signs of hypertension, or high blood pressure, are found in the eyes of around 10{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of the adult, diabetes-free population.

On examination, an eye doctor might see traces of narrowing of arterioles in the retina, arteriovenous nicking, retinal hemorrhages, and, as in diabetic retinopathy, microaneurysms. All these are indicators of hypertensive retinopathy.

“Hypertension also presents with classic signs within the eye. The earliest signs of hypertension are narrowing of the vessels, often referred to as ‘silver wiring’ because of their appearance.”

– Dr. Philip Storey

The good news is that if the hypertension is controlled, the damage can be halted, as Dr. Ibrahim explained.

“Early detection means that appropriate precautions are taken and necessary lifestyle changes are made, such as eating a healthy diet and exercising regularly, in addition to starting the proper medical treatment thereby reducing the risk of heart disease,” she told us.

During a routine eye test, the eye doctor will also examine the optic nerve to look for any abnormalities or changes.

Dr. Ibrahim explained why: “The optic nerve connects the eye to the brain and is therefore an extension of the central nervous system. It is the only part of the brain that can be clearly visualized by examining the back of the eye.”

“Optic nerve swelling or inflammation can be detrimental to vision and color vision, and can diagnose MS, [which is] an autoimmune demyelinating disease of the brain and spinal cord, [as well as] neuroinflammatory disorders such as neuromyelitis optica or brain tumor,” she added.

Vision problems in MS, which tend to flare up then resolve within a few weeks, are usually a result of optic neuritis, an acute inflammatory demyelinating disorder of the optic nerve.

Optic neuritis is the first symptom in up to 20{35112b74ca1a6bc4decb6697edde3f9edcc1b44915f2ccb9995df8df6b4364bc} of people who are subsequently diagnosed with MS, although it can indicate other disorders, or even be the result of a viral infection or vitamin deficiency.

If an optometrist suspects optic neuritis in a routine eye examination, they will refer a person for further testing to confirm the diagnosis and identify the cause.

“Retinal screening of Alzheimer’s disease is an exciting prospect at the forefront of current medical research. The retina […] is made up of multiple layers of specialized neural cells and there is strong evidence that the same changes in the brain can occur in the retina, potentially allowing screening patients for early signs of Alzheimer’s disease.”

– Dr. Hagar Ibrahim

Current methods of diagnosing Alzheimer’s are often lengthy, invasive and expensive, so being able to diagnose the condition from the retina would be a huge advance.

Although this is not yet a disease that can be diagnosed from a routine eye examination, recent research has suggested that doctors could, in the future, diagnose Alzheimer’s through retinal scans.

The new technique, so far tested only in mice, combines the results of two scans to assess the condition of the retina. Those with Alzheimer’s disease have a much rougher retinal surface than those without.

Other research has identified beta-amyloid plaques on the retina as an indication of Alzheimer’s disease, and also in the lens of the eye, both of which can be detected by non-invasive methods.

Dr. Ibrahim explained some of the new developments:

“There are several areas under research. Firstly, looking for the presence of beta-amyloid fragments in the retina, which may be detected by specialist retinal imaging modalities, before symptom onset. […] Secondly, looking at biomarkers detectable on retinal OCT-A images in the form of differences of retinal microvasculature in patients with Alzheimer’s disease and mild cognitive impairment compared to healthy controls.”

Perhaps these findings may lead to easier, earlier diagnosis of Alzheimer’s disease enabling treatment to begin before symptoms become severe.

As well as allowing an optometrist to detect diseases elsewhere in the body, changes in the eyes can tell a physician how a systemic disease is progressing.

So regular eye tests are important, particularly as we get older, as Dr. Benjamin Bert, an ophthalmologist at MemorialCare Orange Coast Medical Center in Fountain Valley, CA, told MNT:

“While eye exams are mostly to check the health of the eyes, they do help to screen for systemic diseases. For adults, if you don’t have any need for glasses or contact lenses, it is still recommended to get an annual exam at least once in your 20s, twice in your 30s, and more regularly after 40. After 40 is when eye-specific ailments can start to become more common — including presbyopia, glaucoma, cataract, and changes to the retina from diabetes or high blood pressure.”

Dr. Krauss reiterated the same advice.

But it is also important to remember that eye examinations are only one tool in monitoring health conditions.

“An examination of the retina often reflects the severity of a disease throughout the body. […] However, patients should not rely on an eye examination to assess how well their systemic disease is controlled,” Dr. Storey cautioned.

“The damage that we see in the eye can take years to occur. Even when a patient’s eye examination is normal, their systemic disease — hypertension or diabetes for example — could be poorly controlled,” he explained.

So, make sure a regular eye test is part of your overall health care, particularly as you get older — it may just detect a condition that you were unaware of, helping you to take control of your health.